ReviewCureus2023
Typical and Atypical Presentations of Appendicitis and Their Implications for Diagnosis and Treatment: A Literature Review.
Review in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 44 citations in OpenAlex.
- Hypertriglyceridemic Acute Pancreatitis With Concomitant Retrocecal Appendicitis: A Case Report.Clinical case reports · 2026Article
- Article
- Path beyond the blind end-unravel the imaging spectrum of appendiceal pathologies.Abdominal radiology (New York) · 2026Review
- Diagnostic Accuracy of Inflammatory Biomarkers in Differentiating Acute Appendicitis From Other Acute Abdomen and Predicting Disease Severity: A Prospective Comparative Cross-Sectional Study.Health science reports · 2026Article
- Perforated Subhepatic Appendicitis Mimicking Hepatobiliary Pathology: A Case Report and Narrative Literature Review.Cureus · 2026Article
- Unveiling Atypical and Uncommon Appendiceal Pathologies in Pediatric Patients With Appendicitis.Cureus · 2026Article
- Evaluation of the predictive value of scoring systems in diagnosis of acute appendicitis: a comparative prospective study.Langenbeck's archives of surgery · 2026Article
- A Hybrid Model with Quantum Feature Map Based on CNN and Vision Transformer for Clinical Support in Diagnosis of Acute Appendicitis.Biomedicines · 2026Article
- Atypical Appendicitis Mimicking Gynecological Pathology: A Diagnostic Challenge in a Middle-Aged Woman.The American journal of case reports · 2026Article
- Jujube pit ingestion leading to ileal perforation and secondary acute appendicitis in a child: a case report.AME case reports · 2026Article
- Diarrhea management: from pathophysiology to microbiota modulation.Therapeutic advances in gastroenterology · 2026Review
- Imaging of appendicitis: Computed tomography, magnetic resonance imaging, and ultrasound in diagnosis and management.World journal of gastrointestinal pathophysiology · 2025Review
- Article
- Artificial intelligence in acute appendicitis: A comprehensive review of machine learning and deep learning applications.World journal of gastroenterology · 2025Review
- Acute subumbilical appendicitis in a patient undiagnosed with intestinal malrotation: a case report.Journal of medical case reports · 2025Article
- Article
- Article
- Application value of abdominal ultrasonography in the diagnosis of pediatric patients aged 3-12 years with acute appendicitis.World journal of gastrointestinal surgery · 2025Article
- Concurrent Acute Appendicitis and Cholecystitis: A Systematic Literature Review.Journal of clinical medicine · 2025Article
- Evaluation of computed tomography (CT) appendicitis score and laboratory parameters in acute appendicitis with and without CT-detected appendicolith.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2025Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Appendicitis, an acute inflammation of the appendix, affects all demographic groups and exhibits various incidences and clinical manifestations. While acute appendicitis typically presents with colicky periumbilical abdominal pain that localizes to the right lower quadrant, atypical presentations are more common in children, geriatric, and pregnant patient populations, leading to delays in diagnosis. Clinical evaluation, clinical scoring systems, and inflammatory markers are commonly used, but their limitations have led to the increased use of diagnostic imaging in patients suspected of appendicitis. Acute appendicitis is managed by non-operative and operative management, depending on whether it is uncomplicated or complicated. Developing diagnostic pathways to improve outcomes and reduce complications is crucial. Although medical advancements have been made, diagnosing and managing appendicitis can be challenging, mainly when patients are present atypically. This literature review aims to comprehensively review typical and atypical presentations of appendicitis and their current implications for diagnosis and treatment modalities in pediatric, adult, pregnant, and geriatric patient populations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.