Evidence map›Paper›PMID 37143539›Full record

ArticleFrontiers in microbiology2023

Traditional mineral medicine realgar and

Lu Luo, Chaofeng Li, Nanxi Huang, Qiaochu Wang, Zihao Zhang, Chen Song, Hui Yang, Maowen Yuan, Ziwen Xu, Jialei Sun and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Lu Luo *Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Chaofeng Li *Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Nanxi HuangDepartment of Biochemistry and Molecular & Cellular Biology, Georgetown University Medical Center, Washington, DC, United States.
Qiaochu WangDepartment of Biochemistry and Molecular & Cellular Biology, Georgetown University Medical Center, Washington, DC, United States.
Zihao ZhangDepartment of Biochemistry and Molecular & Cellular Biology, Georgetown University Medical Center, Washington, DC, United States.
Chen SongInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Hui YangInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Maowen YuanSchool of Earth Science and Resources, China University of Geosciences, Beijing, China.
Ziwen XuDepartment of Biochemistry and Molecular & Cellular Biology, Georgetown University Medical Center, Washington, DC, United States.
Jialei SunThird Affiliated Hospital of Zhejiang University of Traditional Chinese Medicine, Hangzhou, China.
Zhijie ZhangInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Georgetown University · USChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Realgar has a long history ofuse in traditional medicines. However, the mechanism through which Realgar or Methods: In this study, 60 feces and 60 ileum samples from rats administered with realgar or RIF were collected to examine the gut microbiota. Results: The results showed that realgar and RIF influenced different microbiota in both feces and ileum. Compared with realgar, RIF at low dosage (0.1701 g/3 ml) significantly increased the microbiota diversity. LEfSe and random forest analyses showed that the bacterium Discussion: Our results suggest that realgar and RIF may exert their therapeutic effects through influencing microbiota. The low dose of RIF had greater effects on increasing the diversity of microbiota, and

Indexed as

Bacteroidalesgut microbiotamineral medicinerealgarRealgar-Indigo naturalis formula (RIF)

Identifiers

PMID37143539
PMCPMC10151705
OpenAlexW4366290741

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.