ArticlePaediatric and perinatal epidemiology2023
Trends in prenatal diagnosis of congenital anomalies in Western Australia between 1980 and 2020: A population-based study.
Article in Paediatric and perinatal epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed, 11 citations in OpenAlex.
- Temporal trends and maternal factors associated with congenital anomalies among live births in São Paulo, Brazil: a population-based study, 2015-2023.BMC pregnancy and childbirth · 2026Article
- Timing of diagnosis and factors associated with delayed detection of structural birth defects in children: a multicenter cross-sectional study from Addis Ababa, Ethiopia.World journal of pediatric surgery · 2026Article
- Impact of data sources and ascertainment methods on reporting paediatric genetic condition prevalence: A scoping review.Health information management : journal of the Health Information Management Association of Australia · 2026Article
- Global, regional, and national burden of congenital musculoskeletal and limb anomalies, 1990-2021: a systematic analysis of the global burden of disease in 2021.Tropical medicine and health · 2025Article
- Burden of urogenital congenital anomalies: findings from the global burden of disease study 2021.Frontiers in pediatrics · 2025Article
- Adverse Pregnancy and Child Outcomes in Oral Retinoid-Exposed Pregnancies: A Nationwide Population-Based Study.Journal of Korean medical science · 2024Article
- Trends in prenatal diagnosis of congenital anomalies in Western Australia between 1980 and 2020: A population-based study.Paediatric and perinatal epidemiology · 2023Article
- Pattern and Outcome of Congenital Anomalies Seen in the Newborn Unit of a Tertiary Hospital in North-East Nigeria.Nigerian medical journal : journal of the Nigeria Medical AssociationArticle
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5 authors at 2 institutions in 1 country.
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Abstract
backgroundAdvances in screening and diagnostics have changed the way in which we identify and diagnose congenital anomalies.
objectiveTo examine changes in rates of prenatal diagnosis of congenital anomalies over time and by demographic characteristics.
methodsWe undertook a population-based retrospective cohort study of all children born in Western Australia between 1980 and 2020 and diagnosed with a congenital anomaly. Age at diagnosis (prenatal, neonatal, infancy, early childhood or childhood) prevalence (all-type and type-specific), and prevalence ratios (PR) were calculated. We fit joinpoint regression models to describe the average annual percentage change (APC) in prenatal diagnosis over time, and log-binomial regression models to estimate the association between prenatal diagnosis and demographic characteristics.
resultsPrenatal diagnosis prevalence between the first (1980-1989: 28.3 per 10,000 births) and last (2005-2014: 156.1 per 10,000 births) decades of the study increased 5.5-fold (95% confidence interval [CI] 5.0, 5.9). Substantial increases were observed for cardiovascular (PR 10.7, 95% CI 8.0, 14.6), urogenital (PR 10.5, 95% CI: 8.7, 12.6) and chromosomal anomalies (PR 7.0, 95% CI 5.9, 8.3). Prenatal diagnosis was positively associated with the birth year (adjusted risk ratio [RR] 1.04, 95% CI 1.03, 1.04), advanced maternal age (RR 1.14, 95% CI 1.11, 1.18), multiple anomalies (RR 2.86, 95% CI 2.77, 2.96) and major anomalies (RR 3.75, 95% CI 3.36, 4.19), and inversely associated with remoteness (RR 0.89, 95% CI: 0.83, 0.95) and Aboriginality (RR 0.90, 95% CI 0.83, 0.97).
conclusionsIncreases in prenatal diagnosis of congenital anomalies were observed in Western Australia from 1980 to 2020, reflecting advances in screening. Prenatal diagnosis was less common in remote regions and in Aboriginal children, strengthening calls for increased provision of antenatal care services for these populations.
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