ArticleBMC complementary medicine and therapies2023
In vitro antioxidant and free-radical scavenging activities of polar leaf extracts of Vernonia amygdalina.
Article in BMC complementary medicine and therapies, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
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62 citing papers in PubMed, 147 citations in OpenAlex.
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- Comprehensive Characterization of Polyphenols from Salvia chudaei: HPLC-PDA Profiling, in vitro Biological Activities, and in silico Enzyme Interactions.The protein journal · 2026Article
- Processing-induced modulation of nutraceutical and anti-nutritional profiles of beetroot variants targeting enhanced iron retention.Scientific reports · 2026Article
- Methanol extract of Chenopodium murale L. attenuated TNF-α-mediated oxidative stress and inflammation in murine models.Inflammopharmacology · 2026Article
- Ethnobotanical importance and bioactivity of wild herbal teas from District Poonch Azad Jammu and Kashmir.Scientific reports · 2026Article
- Microwave-Induced Structural Remodeling of Legume Proteins: Structure-Function-Nutrition Relationships and Their Improved Performance in Wheat Flour Fortification.Foods (Basel, Switzerland) · 2026Article
- Drimiopsis maculata methanol extract attenuates inflammation in experimental rat model of polyarthritis: a biochemical and molecular insight.Inflammopharmacology · 2026Article
- Bioactivity-Guided Fractionation, Characterization, and Mechanistic Insights of Anticancer Agents fromMolecules (Basel, Switzerland) · 2026Article
- Design and Factorial Optimization of Curcumin and Resveratrol Co-Loaded Lipid Nanocarriers for Topical Delivery.Pharmaceutics · 2026Article
2 more citing papers are in PubMed but not listed here.
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2 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundPlants are able to deliver a huge number of differing bioactive compounds which may supplement the requirements of the human body by acting as natural antioxidants. Antioxidants are mindful for the defense component of the life form against the pathologies related to the assault of free radicals. The main purpose of this study was to investigate the qualitative phytochemical composition of Vernonia amygdalina leaf extract and its antioxidant activity.
methodThe powdered plant sample was successively extracted with aqueous, methanol and ethanol solvents using Soxhlet apparatus. The antioxidant activities of the crude leaf extract were determined using 1, 1- diphenyl-2-picryl hydrazyl (DPPH) radical, 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid (ABTS) radical, phosphomolybdate (PM) and hydrogen peroxide (H
resultsPhytochemical investigation of the plant revealed that the three solvent extracts contained numerous bioactive compounds namely alkaloids, tannins, saponins, phenols, terpenoids, steroids, glycosides and sugars. The result showed that, the leaf extracts of V. amygdalina obtained from methanol extract exhibit the maximum antioxidant activity compared ethanol and aqueous extracts. The IC50 values of DPPH assay for the H
conclusionThis study revealed that V. amygdalina leaf has a noteworthy antioxidant and free radical scavenging activity mitigating the traditional use of the plant for different aliments.
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