ArticleIndian journal of pediatrics2023
Status of Vitamin B12, Zinc, Copper, Selenium, Manganese, Molybdenum and Cobalt in Severe Acute Malnutrition.
Article in Indian journal of pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 9 citations in OpenAlex.
- Combination and Interaction of Seven Trace Elements and the Risk of Protein-Energy Malnutrition in School-Aged Children in Shenzhen, China.Biological trace element research · 2026Article
- Plasma Vitamin B12 May Be a Misleading Biomarker among Children with Severe Acute Malnutrition: An Observation from Mwanza, Tanzania.The Journal of nutrition · 2025Article
- Prevalence and Predictors of Vitamin B12 Deficiency in Children with Severe Acute Malnutrition, and its Association with Development.Indian journal of pediatrics · 2025Article
- Evaluation of Arsenic and Cobalt Levels in Pediatric Patients Receiving Long-Term Parenteral Nutrition.Nutrients · 2024Article
- 'Hidden Hunger' in the Severely Malnourished.Indian journal of pediatrics · 2023Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo define the vitamin B12 levels and other micronutrients status in severe acute malnutrition (SAM) children.
methodsThis was a prospective hospital based cross-sectional study. INCLUSION CRITERIA: Children with severe acute malnutrition as per WHO criteria. EXCLUSION CRITERIA: (i) Pernicious anemia (ii) Autoimmune gastritis (iii) SAM children on exclusive vitamin B12 supplementation. All enrolled children underwent a detailed clinical history, general physical examination with more emphasis on clinical features of vitamin B12 and other micronutrients deficiencies. Three ml of venous blood was collected to estimate vitamin B12 and other micronutrients. Primary outcome was percentage of deficiency of serum vitamin B12, zinc, copper, selenium, manganese, molybdenum and cobalt in SAM children.
resultsFifty children were included in the study. The mean age of children was 15.60±12.90 mo with male to female ratio 0.85:1. The common clinical presentation in order of frequency were upper respiratory infection (URI) symptoms 35 (70%), hepatomegaly 24 (48%), Hyperpigmentation 17 (34%), angular cheilitis 14 (28%), tremors 11 (22%), edema 07 (14%), and hypotonia 05 (10%). Anemia was found in 44 (88%) children. Prevalence of vitamin B12 deficiency was 34%. Other micronutrient deficiencies observed were cobalt 24 (100%), copper 05 (12%), zinc 04 (9.5%), and molybdenum 03 (12.5%). No statistical significance was found between clinical symptoms and levels of vitamin B12 with different age and sex.
conclusionsPrevalence of low vitamin B12 and cobalt were more common than other micronutrients.
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