Evidence map›Paper›PMID 37142525›Full record

SynthesisJournal of cystic fibrosis : official journal of the European Cystic Fibrosis Society2023

Lung function and secondhand smoke exposure among children with cystic fibrosis: A Bayesian meta-analysis.

Jack Reifenberg, Emrah Gecili, Teresa Pestian, Eleni-Rosalina Andrinopoulou, Patrick H Ryan, Cole Brokamp, Joseph M Collaco, Rhonda D Szczesniak

Open access · bronzeAbstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. The Impact of Environmental Pollution and Climate Change on Allergic Rhinitis and Lung Diseases.World journal of otorhinolaryngology - head and neck surgery · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Jack ReifenbergUniversity of Cincinnati, Cincinnati, OH, United States.
Emrah GeciliDivision of Biostatistics & Epidemiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave (MLC 5041), Cincinnati, OH 45229, United States; Department of Pediatrics, University of Cincinnati, Cincinnati, OH, United States.
Teresa PestianDepartment of Anesthesia, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.
Eleni-Rosalina AndrinopoulouDepartment of Biostatistics, Erasmus Medical Center, Rotterdam, the Netherlands; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
Patrick H RyanDivision of Biostatistics & Epidemiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave (MLC 5041), Cincinnati, OH 45229, United States; Department of Pediatrics, University of Cincinnati, Cincinnati, OH, United States.
Cole BrokampDivision of Biostatistics & Epidemiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave (MLC 5041), Cincinnati, OH 45229, United States; Department of Pediatrics, University of Cincinnati, Cincinnati, OH, United States.
Joseph M CollacoDepartment of Pediatrics, Johns Hopkins University, Baltimore, MD, United States.
Rhonda D SzczesniakDivision of Biostatistics & Epidemiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave (MLC 5041), Cincinnati, OH 45229, United States; Department of Pediatrics, University of Cincinnati, Cincinnati, OH, United States; Division of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States. Electronic address: rhonda.szczesniak@cchmc.org.
Cincinnati Children's Hospital Medical Center · USErasmus MC · NLJohns Hopkins University · USUniversity of Cincinnati · US

Funding

R01- Mapping environmental contributions to rapid lung disease progression in cystic fibrosisR01HL141286 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI SZCZESNIAK, RHONDA · 2019 to 2023
$2.3M
NHLBI NIH HHS R01 HL141286
6 · The paper itself

Abstract

backgroundSecondhand smoke exposure, an important environmental health factor in cystic fibrosis (CF), remains uniquely challenging to children with CF as they strive to maintain pulmonary function during early stages of growth and throughout adolescence. Despite various epidemiologic studies among CF populations, little has been done to coalesce estimates of the association between secondhand smoke exposure and lung function decline.

methodsA systematic review was performed using PRISMA guidelines. A Bayesian random-effects model was employed to estimate the association between secondhand smoke exposure and change in lung function (measured as FEV

resultsQuantitative synthesis of study estimates indicated that second-hand smoke exposure corresponded to a significant drop in FEV

Indexed as

Cystic FibrosisTobacco Smoke PollutionAdolescentBayes TheoremChildHumansLungTobacco Smoke PollutionCystic fibrosisEnvironmental healthFEV1Lung functionPediatricPulmonary function testingSecondhand smoke exposureTobacco

Identifiers

PMID37142525
PMCPMC10524940
OpenAlexW4367671091

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.