SynthesisNeuroscience and biobehavioral reviews2023
Interpersonal early adversity demonstrates dissimilarity from early socioeconomic disadvantage in the course of human brain development: A meta-analysis.
Synthesis in Neuroscience and biobehavioral reviews, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Effects of adverse childhood experiences on behavior in adolescence: Insights from brain imaging and genetic risk.Developmental cognitive neuroscience · 2026Article
- Childhood adversity and psychotic-like experiences in adolescence: Investigating a pathway via disrupted pubertal and grey matter development.JCPP advances · 2026Article
- A protocol for the Teen Bugs study: An integrative, multi-omics approach to understanding the role of the gut microbiome and mesocorticolimbic system in adolescent mental health following early adverse caregiving.Brain, behavior, & immunity - health · 2026Article
- Sex-specific associations of childhood adversity with frontostriatal network organization and anhedonia in young adulthood.bioRxiv : the preprint server for biology · 2026Article
- The oral microbiome is associated with stress, adversity, and mental health in young adults.Scientific reports · 2026Article
- Childhood Family Support as a Protective Factor for Adult Mental Health: Does It Hold Under Cumulative Risk?European journal of investigation in health, psychology and education · 2026Article
- Individual differences in adolescent cortical development are associated with neighborhood characteristics: Longitudinal findings from the ABCD study.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Implications for the Prevention of Poverty-Related Environmental Risks for Childhood ADHD: A Narrative Review.Child psychiatry and human development · 2026Review
- Correction: Implications for the Prevention of Poverty-Related Environmental Risks for Childhood ADHD: A Narrative Review.Child psychiatry and human development · 2026Article
- Prefrontal-centered cortical alterations and network dysconnectivity in cocaine use disorder.Frontiers in psychiatry · 2026Article
- Conflict resolution dynamics with stable caregivers confer resilience for youth exposed to early caregiving-related adversity.Development and psychopathology · 2025Article
- Sex-Specific Effects of Early-Life Unpredictability on Hippocampal and Amygdala Responses to Novelty in Adolescents.Biological psychiatry global open science · 2025Article
- Maltreatment effects on cognitive control functional connectivity across adolescence: Prospective links to young adult mental health.Development and psychopathology · 2025Article
- Spontaneous reinstatement of episodic memories in the developing human brain.bioRxiv : the preprint server for biology · 2025Article
- "I take a deep breath first": Adolescent self-regulation and co-regulation in contexts of urban poverty in Bogotá, Colombia.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2025Article
- The influence of deprivation on cortical development and psychotic symptoms in youth.Journal of child psychology and psychiatry, and allied disciplines · 2025Article
- Association of social and environmental exposures at the neighborhood level with child brain volume.Environment international · 2025Article
- Associations of interpersonal and socioeconomic early life adversity dimensions with adolescents' corticolimbic circuits, cognition, and mental health.Translational psychiatry · 2025Article
- Investigative Approaches to Resilient Emotion Regulation Neurodevelopment in a South African Birth Cohort.Biological psychiatry global open science · 2025Article
- Potential for the medial prefrontal cortex to link mentalizing and attachment schemas.Social cognitive and affective neuroscience · 2025Review
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Abstract
It has been established that early-life adversity impacts brain development, but the role of development itself has largely been ignored. We take a developmentally-sensitive approach to examine the neurodevelopmental sequelae of early adversity in a preregistered meta-analysis of 27,234 youth (birth to 18-years-old), providing the largest group of adversity-exposed youth to date. Findings demonstrate that early-life adversity does not have an ontogenetically uniform impact on brain volumes, but instead exhibits age-, experience-, and region-specific associations. Relative to non-exposed comparisons, interpersonal early adversity (e.g., family-based maltreatment) was associated with initially larger volumes in frontolimbic regions until ∼10-years-old, after which these exposures were linked to increasingly smaller volumes. By contrast, socioeconomic disadvantage (e.g., poverty) was associated with smaller volumes in temporal-limbic regions in childhood, which were attenuated at older ages. These findings advance ongoing debates regarding why, when, and how early-life adversity shapes later neural outcomes.
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