Evidence map›Paper›PMID 37141145›Full record

ArticleAmerican journal of physiology. Renal physiology2023

TRPV4 expression in the renal tubule is necessary for maintaining whole body K

Anna Stavniichuk, Kyrylo Pyrshev, Oleg Zaika, Viktor N Tomilin, Mariya Kordysh, Monika Lakk, David Križaj, Oleh Pochynyuk

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Intercalated Cell ClC-K2 Channel Contributes to Systemic ClFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  4. Article
  5. Review
  6. Calcium signalling and transport in the kidney.Nature reviews. Nephrology · 2024
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Anna StavniichukDepartment of Integrative Biology and Pharmacology, The University of Texas Health Science Center, Houston, Texas, United States.
Kyrylo PyrshevDepartment of Integrative Biology and Pharmacology, The University of Texas Health Science Center, Houston, Texas, United States.
Oleg ZaikaDepartment of Integrative Biology and Pharmacology, The University of Texas Health Science Center, Houston, Texas, United States.
Viktor N TomilinDepartment of Integrative Biology and Pharmacology, The University of Texas Health Science Center, Houston, Texas, United States.
Mariya KordyshDepartment of Integrative Biology and Pharmacology, The University of Texas Health Science Center, Houston, Texas, United States.
Monika LakkDepartment of Ophthalmology and Visual Sciences, University of Utah School of Medicine, Salt Lake City, Utah, United States.
David KrižajDepartment of Ophthalmology and Visual Sciences, University of Utah School of Medicine, Salt Lake City, Utah, United States.ORCID 0000-0003-4468-3029
Oleh PochynyukDepartment of Integrative Biology and Pharmacology, The University of Texas Health Science Center, Houston, Texas, United States.ORCID 0000-0002-5397-6897
The University of Texas Health Science Center at Houston · USUniversity of Utah · US

Funding

Utah Center for Clinical and Translational ScienceUL1TR002538 · NCATS · UNIVERSITY OF UTAH · PI HESS, RACHEL, MAJERSIK, JENNIFER JUHL · 2018 to 2022
$26.0M
CTSA UM1 Program at University of UtahUM1TR004409 · NCATS · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI RACHEL HESS, Jennifer Juhl Majersik · 2023 to 2026
$21.9M
University of Utah, Core Vision Research GrantP30EY014800 · NEI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI PAUL STEVEN BERNSTEIN · 2005 to 2026
$14.6M
Replacement of the Flexcell Tension systemR01EY027920 · NEI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI DAVID KRIZAJ · 2017 to 2026
$3.5M
Physiology of ClC-K2/b Cl- channel in the collecting ductR01DK117865 · NIDDK · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI POCHYNYUK, OLEH · 2019 to 2023
$1.7M
Regulation of K+ balance by distal nephron TRPV4 channelR01DK119170 · NIDDK · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI POCHYNYUK, OLEH · 2018 to 2022
$1.7M
Cellular and Molecular Mechanisms that Contribute to Pressure-Induced Retinal Inflammation and PathologyR01EY031817 · NEI · UNIVERSITY OF UTAH · PI KRIZAJ, DAVID · 2021 to 2024
$1.5M
NCATS NIH HHS UL1 TR002538NCATS NIH HHS UM1 TR004409NEI NIH HHS P30 EY014800NEI NIH HHS R01 EY027920NEI NIH HHS R01 EY031817NIDDK NIH HHS R01 DK117865NIDDK NIH HHS R01 DK119170
6 · The paper itself

Abstract

The Ca

Indexed as

HypokalemiaPotassium DeficiencyAdenosine TriphosphatasesAnimalsHomeostasisKidney TubulesKidney Tubules, DistalMiceMice, KnockoutMice, TransgenicTRPV Cation ChannelsAdenosine TriphosphatasesTrpv4 protein, mouseTRPV Cation Channelsdistal tubule K+ transportflow sensitivityhyperkalemiahypokalemiakaliuresis

Identifiers

PMID37141145
PMCPMC10281785
OpenAlexW4368361293

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.