Evidence map›Paper›PMID 37141109›Full record

ArticleAmerican journal of respiratory and critical care medicine2023

Clusterin Neutralizes the Inflammatory and Cytotoxic Properties of Extracellular Histones in Sepsis.

Jean-François Augusto, Céline Beauvillain, Caroline Poli, Léa Paolini, Isabelle Tournier, Pascale Pignon, Simon Blanchard, Laurence Preisser, Raffaella Soleti, Chloé Delépine and 15 more

Abstract read
PubMed Publisher
In one paragraph

Article in American journal of respiratory and critical care medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Regulation of histones in thromboinflammation.Frontiers in immunology · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. CLUSTERINg Circulating Histones in Sepsis.American journal of respiratory and critical care medicine · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

25 authors at 3 institutions in 2 countries.

Jean-François AugustoUniv Angers, Nantes Université, INSERM, CNRS, CRCI2ICAT, Angers, France.ORCID 0000-0003-1498-2132
Céline BeauvillainUniv Angers, Nantes Université, INSERM, CNRS, CRCIICAT, Angers, France.
Caroline PoliUniv Angers, Nantes Université, INSERM, CNRS, CRCIICAT, Angers, France.
Léa PaoliniUniv Angers, Nantes Université, INSERM, CNRS, CRCIICAT, Angers, France.
Isabelle TournierUniv Angers, Nantes Université, INSERM, CNRS, CRCIICAT, Angers, France.
Pascale PignonUniv Angers, Nantes Université, INSERM, CNRS, CRCIICAT, Angers, France.
Simon BlanchardUniv Angers, Nantes Université, INSERM, CNRS, CRCIICAT, Angers, France.ORCID 0000-0002-7953-0455
Laurence PreisserUniv Angers, Nantes Université, INSERM, CNRS, CRCIICAT, Angers, France.
Raffaella SoletiUniv Angers, Nantes Université, INSERM, CNRS, CRCIICAT, Angers, France.
Chloé DelépineUniv Angers, Nantes Université, INSERM, CNRS, CRCIICAT, Angers, France.
Marine MonnierUniv Angers, Nantes Université, INSERM, CNRS, CRCIICAT, Angers, France.
Isabelle DouchetUMR-CNRS, ImmunConcept, University of Bordeaux, Bordeaux, France.
Pierre AsfarService de Médecine Intensive et Réanimation, CHU d'Angers, Angers, France.
François BeloncleService de Médecine Intensive et Réanimation, CHU d'Angers, Angers, France.ORCID 0000-0002-0590-459X
Olivier GuissetService de Médecine Intensive et Réanimation and.
Renaud PrévelService de Médecine Intensive et Réanimation and.
Alain MercatUMR-CNRS, ImmunConcept, University of Bordeaux, Bordeaux, France.
Emeline VinatierUniv Angers, Nantes Université, INSERM, CNRS, CRCIICAT, Angers, France.
Julien GoretUMR-CNRS, ImmunConcept, University of Bordeaux, Bordeaux, France.
Jean-François SubraUniv Angers, Nantes Université, INSERM, CNRS, CRCIICAT, Angers, France.
Dominique CouezUniv Angers, Nantes Université, INSERM, CNRS, CRCIICAT, Angers, France.
Mark R WilsonMolecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, New South Wales, Australia; and.
Patrick BlancoUMR-CNRS, ImmunConcept, University of Bordeaux, Bordeaux, France.
Pascale JeanninUniv Angers, Nantes Université, INSERM, CNRS, CRCIICAT, Angers, France.
Yves DelnesteUniv Angers, Nantes Université, INSERM, CNRS, CRCIICAT, Angers, France.
Centre National de la Recherche Scientifique · FRCentre Hospitalier Universitaire d'Angers · FRUniversity of Wollongong · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antineoplastic AgentsSepsisAnimalsCell DeathClusterinHistonesInflammationMiceAntineoplastic AgentsClusterinHistonescell deathinflammationmolecular chaperonesepsis

Identifiers

PMID37141109
OpenAlexW4368355969

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.