Evidence map›Paper›PMID 37140797›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2023

Methods and Protocols for Using Extracellular Vesicles as Delivery Vehicles in Neuronal Research.

Manjusha Vaidya, Nasif Sayeed, Caroline Hobson, Sandeep Sreerama, Jonhoi Smith, Riya Shah, Kiminobu Sugaya

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Manjusha VaidyaBurnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, FL, USA.
Nasif SayeedBurnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, FL, USA.
Caroline HobsonBurnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, FL, USA.
Sandeep SreeramaBurnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, FL, USA.
Jonhoi SmithBurnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, FL, USA.
Riya ShahBurnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, FL, USA.
Kiminobu SugayaBurnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, FL, USA. ksugaya@ucf.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular vesicles (EVs) transport nucleic acids, proteins, and lipid molecules for intercellular communication. The biomolecular cargo from EVs can modify the recipient cell genetically, physiologically, and pathologically. This innate ability of EVs can be harnessed to deliver the cargo of interest to a specific organ or a cell type. Importantly, due to their ability to cross the blood-brain barrier (BBB), the EVs can be used as delivery vehicles to transport therapeutic drugs and other macromolecules to inaccessible organs such as the brain. Therefore, the current chapter includes laboratory techniques and protocols focusing on the customization of EVs for neuronal research.

Indexed as

Extracellular VesiclesNucleic AcidsBiological TransportBlood-Brain BarrierBrainNucleic AcidsCargo deliveryExosomesExtracellular vesiclesLocalization

Identifiers

PMID37140797

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.