Evidence map›Paper›PMID 37140693›Full record

ArticlePediatric surgery international2023

Beyond image defined risk factors (IDRFs): a delphi survey highlighting definition of the surgical complexity index (SCI) in neuroblastoma.

S Avanzini, P Dall'Igna, K Bjornland, S Braungart, K Cross, P Flores, H O S Gabra, J Gomez-Chacon, S Irtan, P Lobos and 9 more

Abstract read
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Article in Pediatric surgery international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 19 institutions in 13 countries.

S AvanziniPediatric Surgery Department, IRCCS Istituto Giannina Gaslini, Largo G, Gaslini 5, 16147, Genoa, Italy. stefanoavanzini@gaslini.org.
P Dall'IgnaPediatric Surgery, Dipartimento di Medicina di Precisione e Rigenerativa a Area Jonica, Azienda Ospedaliera-Universitaria Consorziale Ospedale Pediatrico Giovanni XXIII, Bari, Italy.
K BjornlandDepartment of Pediatric Surgery, Oslo University Hospital/University of Oslo, Oslo, Norway.
S BraungartDepartment of Paediatric Surgery, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
K CrossGreat Ormond Street Hospital for Children, Specialist Neonatal and Pediatric Surgery, NHS Foundation Trust, London, UK.
P FloresPediatric Surgery Department Garrahan Hospital, Buenos Aires, Argentina.
H O S GabraDepartment of Paediatric Surgery, The Great North Children Hospital, Newcastle University Hospitals Foundation Trust, Newcastle Upon Tyne, UK.
J Gomez-ChaconDepartment of Pediatric Surgery, Surgical Oncology Unit, Hospital Universitario y Politécnico La Fe, Valencia, Spain.
S IrtanDepartment of Visceral Pediatric and Neonatal Surgery, Sorbonne Université, Armand Trousseau Hospital, AP-HP, Paris, France.
P LobosDepartment of Pediatric Surgery, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
A LohDepartment of Paediatric Surgery, KK Women's and Children's Hospital, Singapore, Singapore.
L E MatthyssensDepartment of Gastrointestinal and Pediatric Surgery, Princess Elisabeth Children's Hospital, Ghent University Hospital, Ghent University, Ghent, Belgium.
M MetzelderDepartment of Pediatric and Adolescent Surgery, Medical University of Vienna, Vienna, Austria.
S ParodiScientific Directorate, IRCCS Istituto Giannina Gaslini, Genoa, Italy.
L PioPediatric Surgery Department, IRCCS Istituto Giannina Gaslini, Largo G, Gaslini 5, 16147, Genoa, Italy.
C P Van de VenDepartment of Pediatric Surgery, Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands.
J FuchsDepartment of Pediatric Surgery and Pediatric Urology, University of Tuebingen, Tübingen, Germany.
P D LostyInstitute of Life Course and Medical Sciences, University of Liverpool, Liverpool, UK.
S SarnackiDepartment of Pediatric Surgery, APHP Centre, University Hospital Necker Enfants Malades, University Paris Cité, Paris, France.
Assistance Publique – Hôpitaux de Paris · FRGarrahan Hospital · ARGhent University Hospital · BEGreat Ormond Street Hospital for Children NHS Foundation Trust · GBHospital Italiano de Buenos Aires · ARHospital Universitari i Politècnic La Fe · ESIstituti di Ricovero e Cura a Carattere Scientifico · ITIstituto Giannina Gaslini · ITKK Women's and Children's Hospital · SGLeeds Teaching Hospitals NHS Trust · GBMedical University of Vienna · ATNewcastle University · GBOslo University Hospital · NOOspedale Pediatrico Giovanni XXIII · ITPrincess Máxima Center · NLSt. Jude Children's Research Hospital · USUniversité Paris Cité · FRUniversity of Liverpool · GBUniversity of Tübingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePreoperative evaluation of Image Defined Risk Factors (IDRFs) in neuroblastoma (NB) is crucial for determining suitability for upfront resection or tumor biopsy. IDRFs do not all carry the same weighting in predicting tumor complexity and surgical risk. In this study we aimed to assess and categorize a surgical complexity (Surgical Complexity Index, SCI) in NB resection.

methodsA panel of 15 surgeons was involved in an electronic Delphi consensus survey to identify and score a set of shared items predictive and/or indicative of surgical complexity, including the number of preoperative IDRFs. A shared agreement included the achievement of at least 75% consensus focused on a single or two close risk categories.

resultsAfter 3 Delphi rounds, agreement was established on 25/27 items (92.6%). A severity score was established for each item ranging from 0 to 3 with an overall SCI range varying from a minimum score of zero to a maximum score of 29 points for any given patient.

conclusionsA consensus on a SCI to stratify the risks related to neuroblastoma tumor resection was established by the panel experts. This index will now be deployed to critically assign a better severity score to IDRFs involved in NB surgery.

Indexed as

NeuroblastomaBiopsyHumansPreoperative CareRisk FactorsDelphi surveyNeuroblastomaRisk factorsSurgery

Identifiers

PMID37140693
OpenAlexW4368360611

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.