Evidence map›Paper›PMID 37140688›Full record

ArticleNeurosurgical review2023

Differences in risk factors and outcome after acute stroke in patients with tandem occlusion and those with isolated intracranial occlusion after endovascular treatment.

Shihan Lin, Yongyu Li, Chunyan Lei, Xinlian Zhou, Xiaoyan Zhu, Xinglong Yang, Chun Chen

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Article in Neurosurgical review, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Shihan LinDepartment of Neurology, Hospital of Kunming Medical University, No. 295 Xi Chang Lu, Kunming, 650032, Yunnan Province, China.
Yongyu LiDepartment of Neurology, Hospital of Kunming Medical University, No. 295 Xi Chang Lu, Kunming, 650032, Yunnan Province, China.
Chunyan LeiDepartment of Neurology, Hospital of Kunming Medical University, No. 295 Xi Chang Lu, Kunming, 650032, Yunnan Province, China. leichunyan328@163.com.
Xinlian ZhouDepartment of Neurology, Hospital of Kunming Medical University, No. 295 Xi Chang Lu, Kunming, 650032, Yunnan Province, China.
Xiaoyan ZhuDepartment of Neurology, Hospital of Kunming Medical University, No. 295 Xi Chang Lu, Kunming, 650032, Yunnan Province, China.
Xinglong YangDepartment of Neurology, Hospital of Kunming Medical University, No. 295 Xi Chang Lu, Kunming, 650032, Yunnan Province, China.
Chun ChenDepartment of Neurology, Hospital of Kunming Medical University, No. 295 Xi Chang Lu, Kunming, 650032, Yunnan Province, China.

Funding

middle-aged academic and technical Training Project for High-Level Talents 202105AC160065National Natural Science Foundation of China 82060230Yunnan Training Project for High-Level Talents RLQB20200003
6 · The paper itself

Abstract

objectiveThis study aimed to compare the clinical features, treatment, and clinical outcome of patients with tandem occlusion and isolated intracranial occlusion through endovascular treatment (EVT).

methodsPatients with acute cerebral infarction who received EVT in two stroke centers were retrospectively included. According to MRI or CTA results, the patients were divided into tandem occlusion group or isolated intracranial occlusion group. The baseline data, etiological classification, treatment, post-stroke complications, image features, and clinical outcome were compared. Multivariate logistic regression analysis was used to evaluate the related factors affecting the prognosis of patients with EVT.

resultsAmong 161 patients with acute cerebral infarction, there were 33 cases (20.5%) in the tandem occlusion group and 128 cases (79.5%) in the isolated intracranial occlusion group. Compared with isolated intracranial occlusion, the patients with tandem occlusion had higher rates of large artery atherosclerosis (P = 0.028), symptomatic intracerebral hemorrhage (sICH) (P = 0.023), bilateral infarction (P = 0.042), and longer time for endovascular procedure (P = 0.026). There was no significant statistical difference in 90-day mRS score between the two groups (P = 0.060). Multivariate logistic regression identified the following independent predictors of poor functional outcome: older age, high fasting blood glucose, infarction area > 1/3, and hemorrhagic transformation.

conclusionsCompared with isolated intracranial occlusion, there was not a worse prognosis among patients with tandem occlusion who received EVT.

Indexed as

Brain IschemiaEndovascular ProceduresStrokeCerebral InfarctionHumansInfarctionIntracranial HemorrhagesRetrospective StudiesRisk FactorsTreatment OutcomeAcute cerebral infarctionEndovascular treatmentIsolated intracranial occlusionPrognosisTandem occlusion

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.