Evidence map›Paper›PMID 37140665›Full record

ArticleArchives of virology2023

Epidemiological and genetic characterization of porcine epidemic diarrhea virus in the Mekong Delta, Vietnam, from 2015 to 2017.

Ngoc Hai Nguyen, Tri Minh Huynh, Hien Duc Nguyen, Danh Cong Lai, Minh Nam Nguyen

Abstract read
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Article in Archives of virology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Ngoc Hai NguyenDepartment of Infectious Disease and Veterinary Public Health, Faculty of Animal Science and Veterinary Medicine, Nong Lam University, Quarter 6, Linh Trung Ward, Thu Duc City, HCMC, 700000, Vietnam. nguyenngochai@hcmuaf.edu.vn.
Tri Minh HuynhVemedim Research and Development Center, Can Tho, 94000, Vietnam.
Hien Duc NguyenCollege of Agriculture, Can Tho University, Can Tho, 94000, Vietnam.
Danh Cong LaiDepartment of Infectious Disease and Veterinary Public Health, Faculty of Animal Science and Veterinary Medicine, Nong Lam University, Quarter 6, Linh Trung Ward, Thu Duc City, HCMC, 700000, Vietnam.
Minh Nam NguyenDepartment of Biomedical Engineering, School of Medicine, Vietnam National University Ho Chi Minh City (VNU-HCM), Linh Trung Ward, Thu Duc City, Ho Chi Minh City, 700000, Vietnam. nmnam@medvnu.edu.vn.ORCID http://orcid.org/0000-0001-5596-6222
Nong Lam University Ho Chi Minh City · VNCan Tho University · VNVietnam National University Ho Chi Minh City · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Porcine epidemic diarrhea (PED) virus (PEDV) is a highly contagious virus. PED was first identified in 2008 and has greatly affected the Vietnamese pig production economy. The aim of this study was to investigate the epidemiological and genetic characteristics of PEDV in piglet herds in the Mekong Delta, Vietnam. Diarrheal stool and intestinal samples from 2262 piglets from 191 herds in five provinces were collected to test for the presence of PEDV. Ten PEDV strains were randomly selected for sequencing, and four genes encoding PEDV structural proteins were analyzed. The rates of herds and samples positive for PEDV were 27.23% and 27.72%, respectively. In positive herds, the morbidity and mortality of PEDV-positive piglets were 97.97% and 79.06%, respectively, with most of the infected piglets under 7 days of age. Phylogenetic analysis showed that the 10 PEDV strains from this study clustered with genotype G2 strains from Vietnam and neighboring countries. Many amino acid substitutions were identified in important antigenic regions in the spike protein of the 10 strains when compared to four PEDV vaccine strains. This study provides novel insights into the epidemiology and genetic diversity of circulating PEDV strains, which could facilitate the development of an appropriate and proactive strategy for controlling PED.

Indexed as

Coronavirus InfectionsPorcine epidemic diarrhea virusSwine DiseasesAnimalsDiarrheaMolecular EpidemiologyPhylogenySwineVietnam

Identifiers

PMID37140665
OpenAlexW4368359100

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.