Evidence map›Paper›PMID 37140606›Full record

ReviewDer Nervenarzt2023

[Motoric cognitive risk syndrome-Setting the course for dementia prevention?]

Paula Theobald, Fabian Herold, Thomas Gronwald, Notger G Müller

Abstract readEnglish AbstractReview
In one paragraph

Review in Der Nervenarzt, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Paula TheobaldProfessur für degenerative und chronische Erkrankungen, Bewegung, Fakultät für Gesundheitswissenschaften Brandenburg, Universität Potsdam, Am Mühlenberg 9, 14476, Potsdam, Deutschland. paula.theobald@uni-potsdam.de.
Fabian HeroldProfessur für degenerative und chronische Erkrankungen, Bewegung, Fakultät für Gesundheitswissenschaften Brandenburg, Universität Potsdam, Am Mühlenberg 9, 14476, Potsdam, Deutschland.
Thomas GronwaldProfessur für Sportwissenschaften, Institute of Interdisciplinary Exercise Science and Sports Medicine, MSH Medical School Hamburg, Am Kaiserkai 1, 20457, Hamburg, Deutschland.
Notger G MüllerProfessur für degenerative und chronische Erkrankungen, Bewegung, Fakultät für Gesundheitswissenschaften Brandenburg, Universität Potsdam, Am Mühlenberg 9, 14476, Potsdam, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe predicted increase in adults with dementia will pose a major challenge for the German healthcare system. To mitigate this challenge, the early detection of adults with an increased risk of dementia is crucial. In this context, the concept of motoric cognitive risk (MCR) syndrome has been introduced into the English literature but is currently relatively unknown in German-speaking countries.

objectiveWhat are the characteristics and diagnostic criteria of MCR? What is the impact of MCR on health-related parameters? What is the current state of evidence regarding the risk factors and prevention of the MCR? MATERIAL AND

methodsWe reviewed the English language literature concerning MCR, the associated risk factors, and protective factors, similarities or differences with the concept of mild cognitive impairment (MCI), and its influence on the central nervous system.

resultsThe MCR syndrome is characterized by subjective cognitive impairment and a slower gait speed. Compared to healthy adults, adults with the MCR have a higher risk of dementia, falls, and mortality. Modifiable risk factors provide a starting point for specific multimodal lifestyle-related preventive interventions.

conclusionAs MCR can be easily diagnosed in practical settings, it could become an important concept for the early detection of adults with an increased risk of dementia in German-speaking countries, although further research is necessary to empirically confirm this assumption.

Indexed as

Cognition DisordersCognitive DysfunctionDementiaCognitionGaitHumansRisk FactorsSyndromeCognitionDemographic changeGaitMCIRisk factors

Identifiers

PMID37140606
PMCPMC10575804

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.