Evidence map›Paper›PMID 37140036›Full record

ArticleNucleic acids research2023

antiSMASH 7.0: new and improved predictions for detection, regulation, chemical structures and visualisation.

Kai Blin, Simon Shaw, Hannah E Augustijn, Zachary L Reitz, Friederike Biermann, Mohammad Alanjary, Artem Fetter, Barbara R Terlouw, William W Metcalf, Eric J N Helfrich and 3 more

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1,340 papers.

0numbers the graph read from it
0cells of the map it votes in
1,340citing papers in PubMed
414.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1,340 citing papers in PubMed, 2,069 citations in OpenAlex.

  1. Article
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  3. Review
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  9. Genome-based identification of heavy metal resistance-associated genes in Bacillus enclensis ABF750 isolated from the polluted sediment of Versova Creek.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
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  10. Siderophore-metal complexes in Paraburkholderia phymatum: structure elucidation of phymabactin.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
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  16. Bacterial-derived cyclic lipopeptides suppress dauer arrest inbioRxiv : the preprint server for biology · 2026
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  20. Draft genome sequences of threeMicrobiology resource announcements · 2026
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1,280 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 4 countries.

Kai BlinThe Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kgs.Lyngby, Denmark.ORCID 0000-0003-3764-6051
Simon ShawThe Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kgs.Lyngby, Denmark.
Hannah E AugustijnMolecular Biotechnology, Institute of Biology, Leiden University, Leiden, The Netherlands.ORCID 0000-0002-1862-6699
Zachary L ReitzBioinformatics Group, Wageningen University, Wageningen, The Netherlands.ORCID 0000-0003-1964-8221
Friederike BiermannBioinformatics Group, Wageningen University, Wageningen, The Netherlands.
Mohammad AlanjaryBioinformatics Group, Wageningen University, Wageningen, The Netherlands.ORCID 0000-0001-8420-1325
Artem FetterBioinformatics Group, Wageningen University, Wageningen, The Netherlands.
Barbara R TerlouwBioinformatics Group, Wageningen University, Wageningen, The Netherlands.
William W MetcalfDepartment of Microbiology, University of Illinois Urbana-Champaign, Urbana, IL, USA.ORCID 0000-0002-0182-0671
Eric J N HelfrichInstitute of Molecular Bio Science, Goethe-University Frankfurt, Frankfurt am Main, Germany.
Gilles P van WezelMolecular Biotechnology, Institute of Biology, Leiden University, Leiden, The Netherlands.ORCID 0000-0003-0341-1561
Marnix H MedemaBioinformatics Group, Wageningen University, Wageningen, The Netherlands.
Tilmann WeberThe Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kgs.Lyngby, Denmark.ORCID 0000-0002-8260-5120
Wageningen University & Research · NLNovo Nordisk Foundation · DKGoethe University Frankfurt · DELeiden University · NLLeibniz University Hannover · DEUniversity of Illinois Urbana-Champaign · US

Funding

Discovery, biosynthesis and bioactivity of phosphonic acid natural productsR01GM127659 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI METCALF, WILLIAM W · 2018 to 2024
$2.2M
NIGMS NIH HHS R01 GM127659
6 · The paper itself

Abstract

Microorganisms produce small bioactive compounds as part of their secondary or specialised metabolism. Often, such metabolites have antimicrobial, anticancer, antifungal, antiviral or other bio-activities and thus play an important role for applications in medicine and agriculture. In the past decade, genome mining has become a widely-used method to explore, access, and analyse the available biodiversity of these compounds. Since 2011, the 'antibiotics and secondary metabolite analysis shell-antiSMASH' (https://antismash.secondarymetabolites.org/) has supported researchers in their microbial genome mining tasks, both as a free to use web server and as a standalone tool under an OSI-approved open source licence. It is currently the most widely used tool for detecting and characterising biosynthetic gene clusters (BGCs) in archaea, bacteria, and fungi. Here, we present the updated version 7 of antiSMASH. antiSMASH 7 increases the number of supported cluster types from 71 to 81, as well as containing improvements in the areas of chemical structure prediction, enzymatic assembly-line visualisation and gene cluster regulation.

Indexed as

ComputersSoftwareArchaeaBacteriaGenome, MicrobialMultigene FamilySecondary Metabolism

Identifiers

PMID37140036
PMCPMC10320115
OpenAlexW4368358469

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.