Evidence map›Paper›PMID 37140013›Full record

ArticleHeadache2023

Validity of self-reported migraine in adolescents and children.

Danielle J Kellier, Blanca Marquez de Prado, Dana Haagen, Philip Grabner, Nichelle Raj, Lara Lechtenberg, Gerardo Velasquez, Jesse Y Hsu, John T Farrar, Andrew D Hershey and 1 more

Open access · greenAbstract read
In one paragraph

Article in Headache, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Danielle J KellierPerelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0001-7811-3468
Blanca Marquez de PradoChildren's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Dana HaagenFox Chase Cancer Center, Philadelphia, Pennsylvania, USA.
Philip GrabnerPatient.ly, New York, New York, USA.
Nichelle RajChildren's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Lara LechtenbergChildren's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Gerardo VelasquezUCSF School of Medicine, San Francisco, California, USA.
Jesse Y HsuPerelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
John T FarrarPerelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Andrew D HersheyCincinnati Children's Hospital, Cincinnati, Ohio, USA.ORCID 0000-0002-1598-7536
Christina L SzperkaPerelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0003-4786-8889
Children's Hospital of Philadelphia · USUniversity of Pennsylvania · USCincinnati Children's Hospital Medical Center · USFox Chase Cancer Center · USNational Patient Safety Foundation · USUniversity of California, San Francisco · US

Funding

UPENN HEAL - Pain Clinical Trial Network Specialized Clinical CenterU24NS115691 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI ASHBURN, MICHAEL ALAN, FARRAR, JOHN T · 2019 to 2023
$1.3M
Occipital Nerve Blocks for Acute Treatment of Pediatric MigraineK23NS102521 · NINDS · CHILDREN'S HOSP OF PHILADELPHIA · PI SZPERKA, CHRISTINA LYNCH · 2018 to 2022
$940k
NINDS NIH HHS 3U24NS115691-01S2NINDS NIH HHS K23 NS102521NINDS NIH HHS K23NS102521NINDS NIH HHS U24 NS115691
6 · The paper itself

Abstract

objectiveTo assess agreement for migraine day between self-report and diagnostic guidelines for children and adolescents using a headache diary.

backgroundTrial guidelines recommend prospective collection of headache features and adoption of migraine day as an outcome measure, but there is no clear consensus on the definition of migraine day.

methodsThis is a secondary analysis of data from two projects-a prospective cohort study validating a pediatric scale of treatment expectancy and a clinical trial of occipital nerve blocks to treat status migrainosus. Participants completed a text message-based diary for 4 or 12 weeks (depending on treatment), and a detailed headache assessment on a random 20% of headache days. Using this assessment, we determined whether a headache day qualified for migraine or probable migraine, based on the International Classification of Headache Disorders, 3rd edition (ICHD-3).

resultsOf 122 enrolled children and adolescents, 106 (86.9%) completed ≥1 detailed headache assessment (438 entries). We found moderate agreement between self-reported and ICHD-derived migraine day, with a Cohen's Kappa of 0.50 (positive predictive value [PPV]: 0.66; negative predictive value [NPV]: 0.85; correlation: 0.51). Allowing for ICHD-derived probable migraine significantly increased PPV (0.66 vs. 0.94; 95% CI: 0.57-0.74 vs. 0.90-0.97), but decreased NPV (0.85 vs. 0.293; CI: 0.77-0.90 vs. 0.199-0.40), Cohen's Kappa (0.50 vs. 0.237; CI: 0. 389-0.60 vs. 0.139-0.352), and correlation (r = 0.51 vs. 0.302; CI: 0.41-0.61 vs. 0.192-0.41). Pain severity (OR: 5.7; CI: 2.39-13.8), photophobia (OR: 4.1; CI: 1.02-16.6), and phonophobia (OR: 7.5; CI: 1.95-29.3) were significantly associated with participants' perception of migraine.

conclusionWe found only moderate agreement between self-reported and ICHD-derived migraine day, suggesting both measures are not equal but may represent overlapping aspects of migraine as a disease. This highlights the difficulty of applying ICHD criteria to individual attacks. We recommend greater methodological transparency in future research to avoid readers conflating both measures.

Indexed as

Headache DisordersMigraine DisordersAdolescentChildHeadacheHumansProspective StudiesSelf Reportmigrainemobile healthpain measurementself-report

Identifiers

PMID37140013
PMCPMC10478717
OpenAlexW4368357621

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.