Evidence map›Paper›PMID 37139815›Full record

Trial reportStroke2023

Effect of an Educational Intervention for Primary Stroke Risk Reduction in Ghana and Nigeria: Pilot Randomized Controlled Trial.

Fred Stephen Sarfo, Joshua Odunayo Akinyemi, Reginald Obiako, Michelle Nichols, Adekunle Gregory Fakunle, Nathaniel Adusei, Michael Ampofo, Oyedunni Arulogun, Carolyn Jenkins, Onoja M Akpa and 5 more

Registry-linked trialOpen access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Stroke, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05619406 (Systematic Investigation of Blacks With Stroke - GENOMICS), which is not on this map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05619406 naunknown statusnot on this map

Systematic Investigation of Blacks With Stroke - GENOMICS (SIBS-GENOMICS)

TypeinterventionalSponsorUniversity College Hospital, IbadanRan2022 to 2022Enrolled100ConditionsHypertension, Adult, Dyslipidemias, Physical InactivityArmsRiskometer Application, Routine Clinic Therapy
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Observational
  10. Article
  11. Article
  12. Knowledge and perspectives of community members on risk assessment for stroke prevention using mobile health approaches in Nigeria.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 10 institutions in 4 countries.

Fred Stephen SarfoKwame Nkrumah University of Science and Technology, Kumasi, Ghana (F.S.S., N.A., M.A.).ORCID 0000-0001-7274-5093
Joshua Odunayo AkinyemiUniversity of Ibadan, Nigeria (J.O.A., A.G.F., O.A., O.M.A., R.A., M.O.O.).ORCID 0000-0002-0675-2110
Reginald ObiakoAhmadu Bello University, Zaria, Nigeria (R.O.).ORCID 0000-0003-1769-8110
Michelle NicholsMedical University of South Carolina, Charleston (M.N., C.J.).ORCID 0000-0002-2078-9649
Adekunle Gregory FakunleUniversity of Ibadan, Nigeria (J.O.A., A.G.F., O.A., O.M.A., R.A., M.O.O.).ORCID 0000-0001-8391-9394
Nathaniel AduseiKwame Nkrumah University of Science and Technology, Kumasi, Ghana (F.S.S., N.A., M.A.).
Michael AmpofoKwame Nkrumah University of Science and Technology, Kumasi, Ghana (F.S.S., N.A., M.A.).ORCID 0000-0001-7136-3966
Oyedunni ArulogunUniversity of Ibadan, Nigeria (J.O.A., A.G.F., O.A., O.M.A., R.A., M.O.O.).ORCID 0000-0002-2173-4682
Carolyn JenkinsMedical University of South Carolina, Charleston (M.N., C.J.).ORCID 0000-0001-5506-7657
Onoja M AkpaUniversity of Ibadan, Nigeria (J.O.A., A.G.F., O.A., O.M.A., R.A., M.O.O.).ORCID 0000-0002-5201-512X
Benjamin AribisalaLagos State University, Nigeria (B.A., S.A.).ORCID 0000-0002-6290-1707
Saheed AbdulrasaqLagos State University, Nigeria (B.A., S.A.).ORCID 0000-0003-2679-6871
Rufus AkinyemiUniversity of Ibadan, Nigeria (J.O.A., A.G.F., O.A., O.M.A., R.A., M.O.O.).ORCID 0000-0001-5286-428X
Bruce OvbiageleUniversity of California, San Francisco (B.O.).ORCID 0000-0002-9958-0644
Mayowa O OwolabiUniversity of Ibadan, Nigeria (J.O.A., A.G.F., O.A., O.M.A., R.A., M.O.O.).ORCID 0000-0003-1146-3070
Kwame Nkrumah University of Science and Technology · GHLagos State University · NGLead City University · NGMedical University of South Carolina · USAdekunle Ajasin University · NGAhmadu Bello University · NGLebanese American University · LBMACOM (United States) · USUniversity of California, San Francisco · USUniversity of Ibadan · NG

Funding

South Carolina Clinical & Translational Research Institute (SCTR)UL1TR001450 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T., FLUME, PATRICK A · 2015 to 2024
$41.1M
H3Africa Administrative Coordinating Centre: Enabling and Supporting Genomics and Health Research Capacity Building in AfricaU24HG009780 · NHGRI · UNIVERSITY OF CAPE TOWN · PI SKELTON, MICHELLE · 2017 to 2022
$4.8M
Stroke Investigative Research & Educational Network (SIREN)U54HG007479 · NHGRI · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI OVBIAGELE, BRUCE, OWOLABI, MAYOWA OJO · 2013 to 2017
$4.2M
Phone-based Interventions under Nurse Guidance after Stroke II (PINGS II)R01HL152188 · NHLBI · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI OVBIAGELE, BRUCE, SARFO, FRED STEPHEN · 2020 to 2024
$2.8M
CNV And Stroke (CaNVAS)R01NS114045 · NINDS · UNIVERSITY OF MARYLAND BALTIMORE · PI COLE, JOHN W. · 2020 to 2024
$2.6M
Stroke Minimization through Additive Anti-atherosclerotic Agents in Routine Treatment II StudyR01NS129133 · NINDS · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI BRUCE OVBIAGELE, Fred Stephen Sarfo · 2022 to 2026
$2.5M
African Rigorous Innovative Stroke Epidemiological Surveillance (ARISES)R01NS115944 · NINDS · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI OVBIAGELE, BRUCE, OWOLABI, MAYOWA OJO · 2020 to 2025
$2.2M
Systematic Investigation of Blacks with Stroke - Genomics (SIBS-Genomics) StudyR01NS107900 · NINDS · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI OVBIAGELE, BRUCE, OWOLABI, MAYOWA OJO · 2018 to 2021
$1.8M
Training Africans to Lead and Execute Neurological Trials & Studies (TALENTS)D43TW012030 · FIC · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI OVBIAGELE, BRUCE · 2021 to 2025
$1.2M
Growing Data-science Research in Africa to Stimulate Progress (GRASP)UE5HL172183 · NHLBI · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI FATUMO, SEGUN, OVBIAGELE, BRUCE · 2023 to 2025
$568k
African Neurobiobank for Precision Stroke Medicine - (ELSI) ProjectU01HG010273 · NHGRI · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI AKINYEMI, RUFUS OLUSOLA, ARULOGUN, OYEDUNNI SOLA · 2018 to 2022
$512k
Stroke Minimization Through Additive Anti-atherosclerotic Agents in Routine Treatment (SMAART)R21NS103752 · NINDS · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI OVBIAGELE, BRUCE, SARFO, FRED STEPHEN · 2017 to 2019
$307k
FIC NIH HHS D43 TW012030NCATS NIH HHS UL1 TR001450NHGRI NIH HHS U01 HG010273NHGRI NIH HHS U24 HG009780NHGRI NIH HHS U54 HG007479NHLBI NIH HHS R01 HL152188NHLBI NIH HHS UE5 HL172183NINDS NIH HHS R01 NS107900NINDS NIH HHS R01 NS114045NINDS NIH HHS R01 NS115944NINDS NIH HHS R01 NS129133NINDS NIH HHS R13 NS115395NINDS NIH HHS R21 NS103752
6 · The paper itself

Abstract

backgroundUsing tailored mobile health interventions to improve global vascular risk awareness and control is yet to be investigated for primary stroke prevention in Africa.

methodsThis 2-arm pilot randomized controlled trial involved 100 stroke-free adults with at least 2 vascular risk factors for stroke. Eligible participants were assigned randomly to a control arm offering 1-time counseling (n=50) or a 2-month educational intervention arm (n=50) comprising a stroke video and riskometer app aimed at improving stroke risk factor awareness and health-seeking behavioral modification to control total vascular risk. Reduction in total stroke risk score was the primary outcome while feasibility and process measures were secondary outcomes.

resultsAll enrolled participants completed the 2-month follow-up (retention rate=100%). The mean (SD) age of participants was 59.5 (±12.5) years, 38% were males. The mean change in stroke risk score at 2 months was -11.9% (±14.2) in the intervention arm versus -1.2% (±9.1) in the control arm,

conclusionsThe intervention demonstrated a positive signal of effect over a 2-month period. A definitive clinical trial with a longer duration of follow-up is warranted on the premise of these promising findings from this pilot randomized clinical trial. REGISTRATION: URL: https://www. CLINICALTRIALS: gov; Unique identifier: NCT05619406.

Indexed as

StrokeAdultAgedFemaleGhanaHumansMaleMiddle AgedNigeriaPilot ProjectsRisk Reduction Behaviorblood pressurecardiovascular diseasefeasibilityrandomized clinical trialrisk factors

Identifiers

PMID37139815
PMCPMC10202839
OpenAlexW4368360588

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.