Evidence map›Paper›PMID 37139798›Full record

ArticleGM crops & food2023

Genetically modified DP915635 maize is agronomically and compositionally comparable to non-genetically modified maize.

Jennifer A Anderson, James Mickelson, Brandon J Fast, Nathan Smith, Robert C Pauli, Carl Walker

Open access · goldAbstract read
In one paragraph

Article in GM crops & food, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jennifer A AndersonCorteva Agriscience™, Johnston, IA, USA.
James MickelsonCorteva Agriscience™, Johnston, IA, USA.
Brandon J FastCorteva Agriscience™, Johnston, IA, USA.ORCID 0000-0003-1061-5116
Nathan SmithCorteva Agriscience™, Johnston, IA, USA.ORCID 0000-0003-0501-7584
Robert C PauliCorteva Agriscience™, Johnston, IA, USA.
Carl WalkerCorteva Agriscience™, Johnston, IA, USA.
Corteva (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DP915635 maize was genetically modified (GM) to express the IPD079Ea protein for corn rootworm (Diabrotica spp.) control. DP915635 maize also expresses the phosphinothricin acetyltransferase (PAT) protein for tolerance to glufosinate herbicide and the phosphomannose isomerase (PMI) protein that was used as a selectable marker. A field study was conducted at ten sites in the United States and Canada during the 2019 growing season. Of the 11 agronomic endpoints that were evaluated, two of them (early stand count and days to flowering) were statistically significant compared with the control maize based on unadjusted p-values; however, these differences were not significant after FDR-adjustment of p-values. Composition analytes from DP915635 maize grain and forage (proximates, fiber, minerals, amino acids, fatty acids, vitamins, anti-nutrients, and secondary metabolites) were compared to non-GM near-isoline control maize (control maize) and non-GM commercial maize (reference maize). Statistically significant differences were observed for 7 of the 79 compositional analytes (16:1 palmitoleic acid, 18:0 stearic acid, 18:1 oleic acid, 18:2 linoleic acid, 24:0 lignoceric acid, methionine, and α-tocopherol); however, these differences were not significant after FDR-adjustment. Additionally, all of the values for composition analytes fell within the range of natural variation established from the in-study reference range, literature range, and/or tolerance interval. These results demonstrate that DP915635 is agronomically and compositionally comparable to non-GM maize represented by non-GM near-isoline control maize and non-GM commercial maize.

Indexed as

Amino AcidsZea maysEdible GrainPlants, Genetically ModifiedUnited StatesVitaminsAmino AcidsVitaminsagronomicscompositiongenetically modifiedsafety assessmentsubstantial equivalenceZea mays L.

Identifiers

PMID37139798
PMCPMC10161957
OpenAlexW4368358465

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.