ArticleMalaysian family physician : the official journal of the Academy of Family Physicians of Malaysia2023
COVID-19 related acute limb ischaemia: A case series.
Article in Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed, 3 citations in OpenAlex.
- Before blaming SARS-CoV-2 infection or vaccination for acute peripheral artery occlusion, rule out differential causes.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2023Article
- Coincidental presence of arterial occlusive disease rather than direct association of SARS-CoV-2 infection.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2023Article
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Authors and funding
9 authors at 1 institution in 1 country.
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Abstract
COVID-19 infection or vaccination is rarely associated with arterial occlusive disease of the extremities. The surgical department of a hospital in Johor, Malaysia, recorded a significant increase in the number of COVID-19-related acute limb ischaemia when the rates of COVID-19 were high both locally and internationally. The clinical presentation and management of acute limb ischaemia associated with COVID-19 infection or vaccination are largely underreported in Johor. Herein, we report a case series of 12 patients managed with strategies ranging from purely anticoagulation to catheter-directed thrombolysis and surgical embolectomy. This case series describes the clinical presentation, risk profiles, treatment approaches and limb outcomes of the patients. The amputation rate was high in view of unfavourable factors, including delayed presentation, high-risk factors and severe COVID-19. Three cases of potential COVID-19 vaccine-related acute limb ischaemia were included. COVID-19-related acute limb ischaemia can be minimised with heightened alert, preemptive optimisation with proper hydration and consideration for early prophylactic anticoagulation in high-risk cases.
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