Evidence map›Paper›PMID 37139350›Full record

ArticleJournal of vascular surgery cases and innovative techniques2023

Detection of multivessel calcific disease progression in a patient with chronic limb-threatening ischemia using fluorine-18 sodium fluoride positron emission tomography imaging.

Ting-Heng Chou, Molly K Wynveen, Eleanor T Rimmerman, Surina Patel, Michael R Go, Mitchel R Stacy

Registry-linked trialAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of vascular surgery cases and innovative techniques, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03622359 (Radiotracer Imaging of Skeletal Muscle Perfusion in Patients With Peripheral Artery Disease), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03622359 narecruitingnot on this map

Radiotracer Imaging of Skeletal Muscle Perfusion in Patients With Peripheral Artery Disease

TypeinterventionalSponsorNationwide Children's HospitalRan2017 to 2028Enrolled192ConditionsPeripheral Artery Disease, Diabetes Mellitus, Chronic Limb-Threatening IschemiaArmsSPECT/CT perfusion imaging, PET/CT perfusion imaging
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ting-Heng ChouCenter for Regenerative Medicine, The Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH.
Molly K WynveenCenter for Regenerative Medicine, The Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH.
Eleanor T RimmermanCenter for Regenerative Medicine, The Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH.
Surina PatelCenter for Regenerative Medicine, The Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH.
Michael R GoDivision of Vascular Diseases and Surgery, Department of Surgery, The Ohio State University College of Medicine, Columbus, OH.
Mitchel R StacyCenter for Regenerative Medicine, The Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH.

Funding

Radiotracer-Based Imaging for Quantitative Assessment of Skeletal Muscle Perfusion in Peripheral Artery DiseaseR01HL135103 · NHLBI · YALE UNIVERSITY · PI Mitchel R Stacy · 2017 to 2026
$3.8M
NHLBI NIH HHS R01 HL135103
6 · The paper itself

Abstract

Vascular calcification contributes to morbidity and poor clinical outcomes for patients with peripheral artery disease; however, the traditional assessment of the calcium burden using computed tomography (CT) imaging or angiography represents already established disease. In the present report, we describe a 69-year-old man with chronic limb-threatening ischemia who had undergone positron emission tomography/CT imaging with fluorine-18 sodium fluoride to evaluate the relationship between baseline levels of positron emission tomography-detectable active vascular microcalcification and CT-detectable calcium progression 1.5 years later. CT imaging at follow-up identified progression of existing lesions and the formation of new calcium in multiple arteries that had demonstrated elevated fluorine-18 sodium fluoride uptake 1.5 years earlier.

Indexed as

CalcificationChronic limb-threatening ischemiaDiabetes mellitusPositron emission tomographySodium fluoride

Identifiers

PMID37139350
PMCPMC10149389

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.