ArticleFrontiers in cardiovascular medicine2023
Right ventricle to pulmonary artery coupling after transcatheter aortic valve implantation-Determinant factors and prognostic impact.
Article in Frontiers in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Right ventricular function assessment following transcatheter aortic valve implantation/replacement (TAVI/TAVR): a systematic review and meta-analysis comparing speckle tracking and conventional echocardiographic approaches.Journal of echocardiography · 2026Pooled it
- The prognostic role of right ventricular-pulmonary arterial coupling in aortic stenosis patients undergoing TAVR: a systematic review and meta-analysis.BMC cardiovascular disorders · 2025Pooled it
- Prognostic value of left atrial strain in significant aortic valve disease: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2025Pooled it
- Article
- Clinical Significance of TAPSE/PASP Ratio in Risk Stratification for Aortic Stenosis Patients Undergoing Transcatheter Aortic Valve Replacement.Journal of cardiovascular development and disease · 2025Article
- Clinical Usefulness of Right Ventricular-Pulmonary Artery Coupling in Patients with Heart Failure.Diagnostics (Basel, Switzerland) · 2025Review
- Phosphodiesterase 9A inhibition improves aging-related increase in pulmonary vascular resistance in mice.GeroScience · 2024Article
- Right Ventricle-Pulmonary Artery Coupling in Patients Undergoing Cardiac Interventions.Current cardiology reports · 2024Review
- The influence of transcatheter aortic valve replacement on left atrial mechanics: a systematic review and meta-analysis.European heart journal. Imaging methods and practice · 2024Article
- Prognostic Value of a New Right Ventricular-to-Pulmonary Artery Coupling Parameter Using Right Ventricular Longitudinal Shortening Fraction in Patients Undergoing Transcatheter Aortic Valve Replacement: A Prospective Echocardiography Study.Journal of clinical medicine · 2024Article
- Current trends and latest developments in echocardiographic assessment of right ventricular function: load dependency perspective.Frontiers in cardiovascular medicine · 2024Review
- Evolving perspectives on aortic stenosis: the increasing importance of evaluating the right ventricle before aortic valve intervention.Frontiers in cardiovascular medicine · 2024Review
- Prognostic implication of right ventricular-pulmonary artery coupling in valvular heart disease.Frontiers in cardiovascular medicine · 2024Review
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Authors and funding
14 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Right ventricular (RV) dysfunction and pulmonary hypertension (PH) have been previously associated with unfavorable outcomes in patients with severe aortic stenosis (AS) undergoing transcatheter aortic valve implantation (TAVI), but little is known about the effect of right ventricle (RV) to pulmonary artery (PA) coupling. Our study aimed to evaluate the determinant factors and the prognostic value of RV-PA coupling in patients undergoing TAVI. Methods: One hundred sixty consecutive patients with severe AS were prospectively enrolled, between September 2018 and May 2020. They underwent a comprehensive echocardiogram before and 30 days after TAVI, including speckle tracking echocardiography (STE) for myocardial deformation analysis of the left ventricle (LV), left atrium (LA), and RV function. Complete data on myocardial deformation was available in 132 patients (76.6 ± 7.5 years, 52.5% men) who formed the final study population. The ratio of RV free wall longitudinal strain (RV-FWLS) to PA systolic pressure (PASP) was used as an estimate of RV-PA coupling. Patients were analyzed according to baseline RV-FWLS/PASP cut-off point, determined through time-dependent ROC curve analysis, as follows: normal RV-PA coupling group (RV-FWLS/PASP ≥0.63, Results: A significant improvement of RV-PA coupling was observed early after TAVI (0.75 ± 0.3 vs. 0.64 ± 0.3 before TAVI, Conclusion: Our results confirm that relief of aortic valve obstruction has beneficial effects on the baseline RV-PA coupling, and they occur early after TAVI. Despite significant improvement in LV, LA, and RV function after TAVI, RV-PA coupling remains impaired in some patients, it is mainly related to persistent pulmonary hypertension and is associated with adverse outcomes.
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