ArticleWorld journal of gastrointestinal endoscopy2023
Relationships of hospitalization outcomes and timing to endoscopy in non-variceal upper gastrointestinal bleeding: A nationwide analysis.
Article in World journal of gastrointestinal endoscopy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 5 citations in OpenAlex.
- Timing of endoscopy and its impact on prognosis in patients admitted to the emergency department with upper gastrointestinal bleeding.Irish journal of medical science · 2026Article
- Minutes to Save a Life in Acute GI Bleeding: A Systematic Review of Early vs. Delayed Endoscopy.Cureus · 2025Review
- Personalized Acute Upper GI Bleeding Diagnostics for Patients at Highest Risk for Endoscopy: Real-World Experience of a Novel, Binary, Bedside Gastric Blood Detection Device.Journal of personalized medicine · 2025Article
- Endoscopic intervention for patients of renal insufficiency with upper gastrointestinal bleeding: efficacy evaluation and predictive model construction.BMC gastroenterology · 2025Article
- Inpatient Outcomes of Gastrointestinal Bleeding in Advanced CKD and Kidney Transplant Recipients: A National Analysis 2016-2019.Kidney360 · 2025Article
- A 13-year nationwide analysis of outcomes of non-variceal upper gastrointestinal bleeding in post-bariatric surgery patients.Translational gastroenterology and hepatology · 2025Article
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Authors and funding
21 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe optimal timing of esophagogastroduodenoscopy (EGD) and the impact of clinico-demographic factors on hospitalization outcomes in non-variceal upper gastrointestinal bleeding (NVUGIB) remains an area of active research.
aimTo identify independent predictors of outcomes in patients with NVUGIB, with a particular focus on EGD timing, anticoagulation (AC) status, and demographic features.
methodsA retrospective analysis of adult patients with NVUGIB from 2009 to 2014 was performed using validated ICD-9 codes from the National Inpatient Sample database. Patients were stratified by EGD timing relative to hospital admission (≤ 24 h, 24-48 h, 48-72 h, and > 72 h) and then by AC status (yes/no). The primary outcome was all-cause inpatient mortality. Secondary outcomes included healthcare usage.
resultsOf the 1082516 patients admitted for NVUGIB, 553186 (51.1%) underwent EGD. The mean time to EGD was 52.8 h. Early (< 24 h from admission) EGD was associated with significantly decreased mortality, less frequent intensive care unit admission, shorter length of hospital stays, lower hospital costs, and an increased likelihood of discharge to home (all with
conclusionBased on this large, nationwide study, early EGD in NVUGIB is associated with lower mortality and decreased healthcare usage, irrespective of AC status. These findings may help guide clinical management and would benefit from prospective validation.
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