Evidence map›Paper›PMID 37138761›Full record

ArticleFrontiers in medicine2023

Lamellar macular defects: are degenerative lamellar macular holes truly degenerative?

Grazia Pertile, Daniela Iacovello, Giorgia Maraone, Elisa Bottega, Massimo Guerriero, Emilia Maggio

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Grazia PertileDepartment of Ophthalmology, IRCCS Sacro Cuore Don Calabria Hospital, Verona, Italy.
Daniela IacovelloDepartment of Ophthalmology, IRCCS Sacro Cuore Don Calabria Hospital, Verona, Italy.
Giorgia MaraoneDepartment of Ophthalmology, IRCCS Sacro Cuore Don Calabria Hospital, Verona, Italy.
Elisa BottegaDepartment of Ophthalmology, IRCCS Sacro Cuore Don Calabria Hospital, Verona, Italy.
Massimo GuerrieroDepartment of Ophthalmology, IRCCS Sacro Cuore Don Calabria Hospital, Verona, Italy.
Emilia MaggioDepartment of Ophthalmology, IRCCS Sacro Cuore Don Calabria Hospital, Verona, Italy.
Ospedale Sacro Cuore Don Calabria · ITIstituti di Ricovero e Cura a Carattere Scientifico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To investigate morpho-functional changes after surgical treatment for ERM foveoschisis or lamellar macular hole (LMH), and to evaluate whether the two entities are associated with different healing processes and long-term outcomes. Design: Retrospective interventional case series. Methods: A total of 56 eyes, treated for lamellar macular defects and followed up for 24 months, were enrolled. The eyes were divided into two groups: 34 with ERM foveoschisis and 22 with LMH. Changes in the following features were evaluated and compared between the two groups: best-corrected visual acuity (BCVA), external limiting membrane (ELM) and ellipsoid zone (EZ) defects, central foveal thickness (CFT), and autofluorescence (FAF) diameter and area. Results: After surgery, progressive BCVA improvement was observed with no significant difference between the two groups ( Conclusion: In the present study, significant functional and microstructural improvements were observed after surgery for both ERM foveoschisis and LMH, demonstrating considerable repair potential in both types of lamellar defects. These findings question the true "degenerative" nature of LMH.

Indexed as

ERM foveoschisishealing processlamellar macular holemacular defectvitrectomy

Identifiers

PMID37138761
PMCPMC10149835
OpenAlexW4366224124

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.