Evidence map›Paper›PMID 37138716›Full record

ArticleThe Canadian veterinary journal = La revue veterinaire canadienne2023

Serum concentrations of brain-derived neurotrophic factor as a potential biomarker of swine welfare.

Hannah R Golightly, Jennifer Brown, Matéa David-Steel, Renée Bergeron, Zvonimir Poljak, Yolande M Seddon, Terri L O'Sullivan

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in The Canadian veterinary journal = La revue veterinaire canadienne, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hannah R GolightlyOntario Veterinary College, Department of Population Medicine (Golightly, David-Steel, Poljak, O'Sullivan) and Ontario Agricultural College, Department of Animal Biosciences (Bergeron), University of Guelph, 50 Stone Road East, Guelph, Ontario N1G 2W1; Prairie Swine Centre, 2105 8th Street East, Saskatoon, Saskatchewan S7H 5N9 (Brown); Western College of Veterinary Medicine, Department of Large Animal Clinical Sciences, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4 (Seddon).
Jennifer BrownOntario Veterinary College, Department of Population Medicine (Golightly, David-Steel, Poljak, O'Sullivan) and Ontario Agricultural College, Department of Animal Biosciences (Bergeron), University of Guelph, 50 Stone Road East, Guelph, Ontario N1G 2W1; Prairie Swine Centre, 2105 8th Street East, Saskatoon, Saskatchewan S7H 5N9 (Brown); Western College of Veterinary Medicine, Department of Large Animal Clinical Sciences, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4 (Seddon).
Matéa David-SteelOntario Veterinary College, Department of Population Medicine (Golightly, David-Steel, Poljak, O'Sullivan) and Ontario Agricultural College, Department of Animal Biosciences (Bergeron), University of Guelph, 50 Stone Road East, Guelph, Ontario N1G 2W1; Prairie Swine Centre, 2105 8th Street East, Saskatoon, Saskatchewan S7H 5N9 (Brown); Western College of Veterinary Medicine, Department of Large Animal Clinical Sciences, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4 (Seddon).
Renée BergeronOntario Veterinary College, Department of Population Medicine (Golightly, David-Steel, Poljak, O'Sullivan) and Ontario Agricultural College, Department of Animal Biosciences (Bergeron), University of Guelph, 50 Stone Road East, Guelph, Ontario N1G 2W1; Prairie Swine Centre, 2105 8th Street East, Saskatoon, Saskatchewan S7H 5N9 (Brown); Western College of Veterinary Medicine, Department of Large Animal Clinical Sciences, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4 (Seddon).
Zvonimir PoljakOntario Veterinary College, Department of Population Medicine (Golightly, David-Steel, Poljak, O'Sullivan) and Ontario Agricultural College, Department of Animal Biosciences (Bergeron), University of Guelph, 50 Stone Road East, Guelph, Ontario N1G 2W1; Prairie Swine Centre, 2105 8th Street East, Saskatoon, Saskatchewan S7H 5N9 (Brown); Western College of Veterinary Medicine, Department of Large Animal Clinical Sciences, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4 (Seddon).
Yolande M SeddonOntario Veterinary College, Department of Population Medicine (Golightly, David-Steel, Poljak, O'Sullivan) and Ontario Agricultural College, Department of Animal Biosciences (Bergeron), University of Guelph, 50 Stone Road East, Guelph, Ontario N1G 2W1; Prairie Swine Centre, 2105 8th Street East, Saskatoon, Saskatchewan S7H 5N9 (Brown); Western College of Veterinary Medicine, Department of Large Animal Clinical Sciences, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4 (Seddon).
Terri L O'SullivanOntario Veterinary College, Department of Population Medicine (Golightly, David-Steel, Poljak, O'Sullivan) and Ontario Agricultural College, Department of Animal Biosciences (Bergeron), University of Guelph, 50 Stone Road East, Guelph, Ontario N1G 2W1; Prairie Swine Centre, 2105 8th Street East, Saskatoon, Saskatchewan S7H 5N9 (Brown); Western College of Veterinary Medicine, Department of Large Animal Clinical Sciences, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4 (Seddon).
Genome Prairie · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Describe concentrations of brain-derived neurotrophic factor (BDNF) detectable in piglet sera before and after road transport, and evaluate the correlation of serum BDNF with other physiological parameters used to assess swine welfare. Animals: Commercial crosses of piglets that underwent weaning and transport at approximately 3 wk of age. Procedure: Sixteen piglets were randomly selected from a larger study for complete blood counts, serum biochemistry testing, cortisol assays, and BDNF assays. Samples were collected 1 d before transport and immediately after transport (> 30 h) under commercial conditions. We assessed the change in serum BDNF concentration; and the correlations between serum BDNF and serum cortisol, neutrophil to lymphocyte ratios (N:L), glucose, and hematological indicators of muscle fatigue. Results: Serum BDNF concentrations increased after transport ( Conclusions: Serum BDNF may be used as an additional indicator of swine welfare. Further research characterizing piglet BDNF concentrations in response to conditions promoting positive or negative affective states would be valuable. Clinical relevance: This communication discusses common hematological parameters used to quantify changes in pig welfare and introduces BDNF, which is a parameter of interest in human cognitive functioning research that may be useful for evaluating the effect of exposure to beneficial or aversive stimuli in animals. The implications of variation in sample collection, handling, and storage procedures for BDNF detection are highlighted.

Indexed as

Brain-Derived Neurotrophic FactorHydrocortisoneAnimalsSwineBrain-Derived Neurotrophic FactorHydrocortisone

Identifiers

PMID37138716
PMCPMC10150563
OpenAlexW4368357886

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.