Evidence map›Paper›PMID 37138532›Full record

ReviewTechnology in cancer research & treatment

Recent Advances in Photothermal Therapies Against Cancer and the Role of Membrane Transporter Modulators on the Efficacy of This Approach.

Ahmed A Abdulhussein Al-Ali, Nameer Al Ward, Mohammad A Obeid, Carsten Uhd Nielsen, Paul A Mulheran, Mohammed M Al Qaraghuli

Open access · goldAbstract readReview
In one paragraph

Review in Technology in cancer research & treatment. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Ahmed A Abdulhussein Al-AliDepartment of Physics, Chemistry and Pharmacy, University of Southern Denmark, Odense M, Denmark.
Nameer Al WardDepartment of Pharmacy, Sultan Qaboos Comprehensive Cancer Care & Research Centre, Muscat, Sultanate of Oman.ORCID 0000-0001-5266-961X
Mohammad A ObeidStrathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK.
Carsten Uhd NielsenDepartment of Physics, Chemistry and Pharmacy, University of Southern Denmark, Odense M, Denmark.
Paul A MulheranDepartment of Chemical and Process Engineering, University of Strathclyde, Glasgow, UK.
Mohammed M Al QaraghuliStrathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK.ORCID 0000-0003-1823-6671
University of Southern Denmark · DKUniversity of Strathclyde · GBEngineering and Physical Sciences Research Council · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, much research is focused on the use of photothermal therapy (PTT) as an advanced method to treat various types of cancer. The PTT approach primarily utilizes nanoparticles (NPs) made from metals, carbon, or semiconductors that can convert near-infrared laser irradiation, which penetrates tissues, into local heat that induces cancer cell death. An alternative approach is to utilize NPs (such as liposomes) to carry suitable dye molecules to the same end. Numerous studies concerning PTT have shown that local heat released in cancer cells may suppress the expression of membrane transporter proteins such as P-glycoprotein (P-gp) and multidrug resistance-associated protein 1 (MRP1), thus enhancing cytotoxicity and reverse multidrug resistance. In addition, because NPs may be loaded with different substances, researchers have designed multifunctional NPs for PTT by including several agents such as membrane transporter modulators, anticancer drugs, and photothermal agents. This review will focus on the recent advances in PTT utilizing various types of NPs, and their components and characteristics. In addition, the role of membrane transporters in PTT will be highlighted and different methods of transporter modulation will be summarized from several PTT studies in which multifunctional NPs were used to treat cancers

Indexed as

NanoparticlesNeoplasmsCell Line, TumorHumansInfrared RaysMembrane Transport ProteinsPhototherapyPhotothermal TherapyMembrane Transport Proteinsand membrane transportersgold nanoparticlesmonoclonal antibodiesphotothermal therapy

Identifiers

PMID37138532
PMCPMC10161341
OpenAlexW4368361418

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.