Observational studyBMC ophthalmology2023
Comparison of corneal measurements in normal and keratoconus eyes using Anterior Segment Optical Coherence Tomography (AS-OCT) and Pentacam HR topographer.
Observational study in BMC ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 11 citations in OpenAlex.
- Preclinical Safety and Feasibility Study of Line-Field Confocal Optical Coherence Tomography for Ophthalmology Applications.Translational vision science & technology · 2026Article
- Article
- Comparison of corneal thickness measured using the new Revo FC optical coherence tomographer and the pentacam Scheimpflug-based imaging system.BMC ophthalmology · 2026Article
- Comparison of corneal pachymetry evolution after accelerated corneal crosslinking in keratoconus eyes using anterior segment optical coherence tomography and Scheimpflug imaging.International ophthalmology · 2025Article
- Anterior Segment OCT Thickness Difference Maps for Monitoring Corneal Thickness Changes: Small-Incision Lenticule Extraction as a Model.Translational vision science & technology · 2025Article
- Machine learning-assisted early detection of keratoconus: a comparative analysis of corneal topography and biomechanical data.Scientific reports · 2025Article
- Application of multimodal large language models for safety indicator calculation and contraindication prediction in laser vision correction.NPJ digital medicine · 2025Article
- Reproducibility and Screening Capability of Corneal Epithelial Thickness Measurement for Keratoconus Using Anterior Segment Optical Coherence Tomography.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- Comprehensive evaluation of oculus pentacam in subclinical keratoconus and clinical keratoconus patients at different stages.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological SocietyArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundKeratoconus (KC) is easily recognized by its unique topographic pattern, but it can be difficult to distinguish subclinical form of the disease from the normal cornea. Optovue anterior segment optical coherence tomography (AS-OCT) helps diagnose KC. AIM OF THE WORK: To assess and the level of agreement of Keratometry-readings (K), Central Corneal Thickness (CCT) and Thinnest Corneal Thickness (TCT) measurements obtained by Optovue AS-OCT and Wavelight Oculyzer Pentacam HR in two groups: KC eyes and normal eyes. PATIENTS AND
methodsThis is a prospective clinical observational study. The study included 110 eyes divided into two groups. The study group included 62 eyes with topographic evidence of KC. The control group included 48 eyes of normal subjects with no topographic evidence of KC. All of the participants underwent full cycloplegic refraction, spectacle best-corrected distance visual acuity, comprehensive slit-lamp biomicroscopy and fundoscopy. All participants underwent corneal topography by Pentacam HR and AS-OCT.
resultsThere were highly significant differences between the studied groups as regarding BCVA, intraocular pressure and CCT measurements which were found to be lower among KC group compared to the control one. There were highly significant differences between the studied groups regarding TCT measurement detected by Pentacam HR and AS-OCT which was found to be lower among the keratoconus group compared to the control one (470.9, 455.7 versus 541.9 and 518.7 respectively).
conclusionBoth Scheimpflug-based imaging and AS-OCT provide comparable readings with a good agreement regarding corneal pachymetry in keratoconus group with accurate identification of KC eyes and healthy ones. However, there was a significant difference in K readings between both devices in Keratoconus and control group.
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