ArticleScientific reports2023
Investigation of composition, antioxidant, antimicrobial and cytotoxic characteristics from Juniperus sabina and Ferula communis extracts.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Comparative phytochemical profiling and meta‑analysis of public transcriptomic datasets uncover species‑ and organ‑specific patterns of flavonoid and phenolic biosynthesis in Ferula species.BMC plant biology · 2026Pooled it
- Optimization and HPLC-DAD Characterization of Phenolic Compounds and Antioxidant Activity inMolecules (Basel, Switzerland) · 2026Article
- Solvent-Based Extraction Recovers Phytochemicals from Medicinal Plants Demonstrating Anticancer and Chemopreventive Potential: A Review.Molecules (Basel, Switzerland) · 2026Review
- Exogenous regulators enhance strawberry yield under heat stress conditions.Scientific reports · 2026Article
- Bioactive compounds and therapeutic potential of Salvia fruticosa Mill. leaves against microorganisms and osteosarcoma.Scientific reports · 2025Article
- Design and Evaluation of aPharmaceutics · 2025Article
- Wild-Grown RomanianPolymers · 2025Article
- Phytochemistry, Pharmacology, and Traditional Medicine Applications ofMolecules (Basel, Switzerland) · 2024Review
- Computational exploration of palmitoyl-protein thioesterase 1 inhibition byJournal of Taibah University Medical Sciences · 2024Article
- Recent Progress in Terrestrial Biota Derived Antibacterial Agents for Medical Applications.Molecules (Basel, Switzerland) · 2024Review
- Insight into Romanian Wild-GrownAntibiotics (Basel, Switzerland) · 2024Article
- Effects of age and tissue ofFrontiers in plant science · 2023Article
Corrections and comments
- Erratum issued
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plants have been one the most valuable sources of biologically active compounds. This study investigates the chemical composition, as well as the antioxidant, antimicrobial, and cytotoxic activities of methanolic and ethanolic extracts from Juniperus sabina and Ferula communis leaves, grown in Cyprus. Total phenolic and flavonoids content of methanol and ethanol extracts were quantified. Chemical constituents of the leaf extracts were analysed using gas chromatography/mass spectrometry (GC/MS). Mome inositol was the predominant component in the J. Sabina's extracts. The most dominant component in F. communis ethanolic extract was phytol, while in FCL methanolic extract 1,3,4,5 tetrahydroxycyclohexanecarboxylic acid. Antioxidant activities were evaluated by 1, 1-diphenyl-2-picrylhydrazyl (DPPH) free radical-scavenging ability. Antioxidant activity results revealed concentration dependent activity for methanolic and ethanolic extracts from the plant leaves. Antibacterial activity of plant extracts was tested against Gram-negative and Gram-positive bacteria using disk diffusion and minimal inhibitory concentration methods. Cytotoxic activity of plant extracts were evaluated on MCF-7 and MDA-MB-231 breast cancer cell lines, where they demonstrated their potential on the viability of both cell lines. The biological activity revealed by plants is due to the bioactive compounds found in the extracts. These bioactive components could be used as anticancer drug candidates.
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