Evidence map›Paper›PMID 37137762›Full record

ArticleTransplantation proceedings2023

Effect of COVID-19 Pandemic on Patients Who Have Undergone Liver Transplantation Because of Hepatocellular Carcinoma.

Sami Akbulut, Nazlican Bagci, Musap Akyuz, Ibrahim Umar Garzali, Hasan Saritas, Murat Tamer, Volkan Ince, Selver Unsal, Ali Aloun, Sezai Yilmaz

Open access · greenAbstract read
In one paragraph

Article in Transplantation proceedings, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Sami AkbulutDepartment of Surgery and Liver Transplant Institute, Inonu University Faculty of Medicine, Malatya, Turkey. Electronic address: akbulutsami@gmail.com.
Nazlican BagciDepartment of Surgical Nursing, Inonu University Faculty of Nursing, Malatya, Turkey.
Musap AkyuzDepartment of Surgical Nursing, Inonu University Faculty of Nursing, Malatya, Turkey.
Ibrahim Umar GarzaliDepartment of Surgery, Aminu Kano Teaching Hospital, Kano, Nigeria.
Hasan SaritasDepartment of Surgical Nursing, Inonu University Faculty of Nursing, Malatya, Turkey.
Murat TamerDepartment of Nursing Service, Inonu University Faculty of Medicine, Malatya, Turkey.
Volkan InceDepartment of Surgery and Liver Transplant Institute, Inonu University Faculty of Medicine, Malatya, Turkey.
Selver UnsalDepartment of Nursing Service, Inonu University Faculty of Medicine, Malatya, Turkey.
Ali AlounKing Hussein Medical Center, Royal Medical Services, Amman, Jordan.
Sezai YilmazDepartment of Surgery and Liver Transplant Institute, Inonu University Faculty of Medicine, Malatya, Turkey.
Inonu University · TRAminu Kano Teaching Hospital · NGKing Hussein Medical Center · JO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimMany clinical studies have shown that the COVID-19 case fatality rate is higher in older patients, those with comorbidities, those with immunosuppressive conditions, and those who stay in the intensive care unit. This study aims to evaluate the clinical outcomes of 66 liver transplant (LT) patients with primary liver cancer who were exposed to COVID-19 infection.

methodsDemographic and clinical data of 66 patients with primary liver cancer (hepatocellular carcinoma = 64, hepatoblastoma = 1, cholangiocarcinoma = 1) who underwent LT in our institute and were exposed to COVID-19 infection between March 2020 and November 2021 were analyzed in this cross-sectional study. The following data of the patients were recorded: age, sex, body mass index (kg/m

resultsThere were 55 (83.3%) male and 11 (16.7%) female patients, with a median age of 58 years. Sixty-four patients were exposed to COVID-19 only once, whereas the remaining 2 patients were exposed 2 and 4 times, respectively. After exposure to COVID-19, it was determined that 37 patients used antiviral drugs, 25 were hospitalized, 9 were followed in the intensive care unit, and 3 were intubated. One intubated patient was under hospital follow-up because of biliary complications before exposure to COVID-19, and this patient died from sepsis.

conclusionThe low mortality rate of LT patients with primary liver cancer exposed to COVID-19 infection can be attributed to background immunosuppression that prevents cytokine storm. However, it is appropriate to support this study with multicenter studies to make strong comments on this issue.

Indexed as

Carcinoma, HepatocellularCOVID-19Liver NeoplasmsLiver TransplantationAgedCross-Sectional StudiesFemaleHumansImmunosuppressive AgentsMaleMiddle AgedPandemicsSARS-CoV-2Immunosuppressive Agents

Identifiers

PMID37137762
PMCPMC10028347
OpenAlexW4328101891

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.