Evidence map›Paper›PMID 37137546›Full record

ArticleBMJ case reports2023

Surgical management of spontaneous bowel perforation and fascial dehiscence in a patient on bevacizumab and pembrolizumab in the setting of active

Mujtaba Mubashir, Brian Tang, Robert L DeBernardo, Xiaoxi Feng

Open access · greenAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mujtaba MubashirGeneral Surgery, Cleveland Clinic, Cleveland, Ohio, USA mujtabamubashir@gmail.com.ORCID http://orcid.org/0000-0002-1387-0684
Brian TangGeneral Surgery, Cleveland Clinic, Cleveland, Ohio, USA.
Robert L DeBernardoObstetrics and Gynecology and Women's Health Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Xiaoxi FengGeneral Surgery, Cleveland Clinic, Cleveland, Ohio, USA.
Cleveland Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunotherapy such as bevacizumab and pembrolizumab is used to treat an increasing number of malignancies. These medications have been associated with poor wound healing and several gastrointestinal complications, including intestinal perforations in rare cases. We present a unique case of a patient with metastatic cervical cancer on pembrolizumab and recent bevacizumab therapy, presenting with a colonic perforation requiring urgent exploratory laparotomy, in the setting of active

Indexed as

Intestinal PerforationAntibodies, Monoclonal, HumanizedBevacizumabFasciaFemaleHumansLaparotomySurgical MeshSurgical Wound DehiscenceAntibodies, Monoclonal, HumanizedBevacizumabpembrolizumabDrug therapy related to surgeryGastrointestinal surgeryGynecological cancerSurgical oncologyUnwanted effects / adverse reactions

Identifiers

PMID37137546
PMCPMC10163437
OpenAlexW4368318055

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.