SynthesisEuropean respiratory review : an official journal of the European Respiratory Society2023
Identifying risk factors for COPD and adult-onset asthma: an umbrella review.
Synthesis in European respiratory review : an official journal of the European Respiratory Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
91 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Associations of the systemic immune-inflammation index and systemic inflammatory response index with chronic obstructive pulmonary disease: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Meat Consumption Associated with the Risk of Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis.Nutrients · 2025Pooled it
- Influence of cigarette smoking on drugs' metabolism and effects: a systematic review.European journal of clinical pharmacology · 2025Pooled it
- Prevalence of respiratory symptoms and associated factors among sanitation workers in Sub Saharan Africa: a systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- Combined Lifestyle Interventions in the Prevention and Management of Asthma and COPD: A Systematic Review.Nutrients · 2024Pooled it
- Precision nanomedicine for pulmonary diseases: from molecular targeting to clinical translation.Signal transduction and targeted therapy · 2026Review
- Low appendicular muscle mass and the risk of COPD development in people with PRISm.ERJ open research · 2026Article
- The shifting landscape of asthma in the United States: An over 20-year analysis of prevalence, severity, and medication paradigms, 1999-2023.The World Allergy Organization journal · 2026Article
- Article
- Prevalence of PRISm and COPD and associated factors in a university medical centre spirometry unit: a cross-sectional analysis.BMJ open · 2026Article
- Genetic and epidemiological evidence linking respiratory and musculoskeletal diseases: shared risk factors and intervention windows.Respiratory research · 2026Article
- Dietary vitamin K intakes, chronic obstructive pulmonary disease, adult asthma, and lung function: a prospective cohort study in the UK Biobank.The American journal of clinical nutrition · 2026Article
- AHNAK promotes oxidative stress and inflammatory responses in chronic obstructive pulmonary disease by activating the Notch pathway.Journal of thoracic disease · 2026Article
- Joint Associations of Outdoor Nitrogen Dioxide and Temperature with Incident Adult-Onset Asthma in the United States.medRxiv : the preprint server for health sciences · 2026Article
- Demographic trends and mortality disparities in emphysema across the United States (1999-2023): a retrospective population-based study using CDC WONDER database.Annals of medicine and surgery (2012) · 2026Article
- The evolving global burden of asthma among children and adolescents, 1990-2040: trends, disparities, and future projections based on Global Burden of Disease (GBD) 2021.Journal of thoracic disease · 2026Article
- Impact of socioeconomic status and lifestyle factors on incidence of COPD and hospital readmissions: 13.7-year follow-up in UK Biobank.BMC public health · 2026Article
- 25-Hydroxyvitamin D Deficiency Elevates the Risk of COPD Incidence and Mortality: A Large Population-Based Prospective Cohort Study.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2026Article
- Prediction of Chronic Obstructive Pulmonary Disease Using Machine Learning, Clinical Summary Notes, and Vital Signs: A Single-Center Retrospective Cohort Study in the United States.Advances in respiratory medicine · 2026Article
- Prevalence, Associate Factors, and Disease Awareness of Chronic Obstructive Pulmonary Disease: A Large-Scale Cross-Sectional Epidemiological Survey.International journal of chronic obstructive pulmonary disease · 2026Article
31 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCOPD and adult-onset asthma (AOA) are the most common noncommunicable respiratory diseases. To improve early identification and prevention, an overview of risk factors is needed. We therefore aimed to systematically summarise the nongenetic (exposome) risk factors for AOA and COPD. Additionally, we aimed to compare the risk factors for COPD and AOA.
methodsIn this umbrella review, we searched PubMed for articles from inception until 1 February 2023 and screened the references of relevant articles. We included systematic reviews and meta-analyses of observational epidemiological studies in humans that assessed a minimum of one lifestyle or environmental risk factor for AOA or COPD.
resultsIn total, 75 reviews were included, of which 45 focused on risk factors for COPD, 28 on AOA and two examined both. For asthma, 43 different risk factors were identified while 45 were identified for COPD. For AOA, smoking, a high body mass index (BMI), wood dust exposure and residential chemical exposures, such as formaldehyde exposure or exposure to volatile organic compounds, were amongst the risk factors found. For COPD, smoking, ambient air pollution including nitrogen dioxide, a low BMI, indoor biomass burning, childhood asthma, occupational dust exposure and diet were amongst the risk factors found.
conclusionsMany different factors for COPD and asthma have been found, highlighting the differences and similarities. The results of this systematic review can be used to target and identify people at high risk for COPD or AOA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.