ArticleCell metabolism2023
Do flies dream of protein? How the gut regulates sleep depth.
Article in Cell metabolism, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
A recent study by Titos et al. in Cell shows that protein-rich diets are strong modulators of sleep depth in Drosophila and identifies the gut-secreted neuropeptide CCHa1 as the mediator of this effect. In the brain, CCHa1 controls dopamine release from a small set of neurons, thereby modulating arousability by integrating internal state with sensory information.
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