Evidence map›Paper›PMID 37134072›Full record

ArticleJournal of veterinary internal medicine

Oculosystemic pneumocystosis in 2 sibling Chihuahuas.

Lynelle R Johnson, Sean E Hulsebosch, Austin K Viall, Patrizia Danesi, Kevin D Woolard, Sarah E Cook, David J Maggs, Brian C Leonard

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Meta-Analysis and Systematic Literature Review of the GenusJournal of fungi (Basel, Switzerland) · 2023
    Article
  3. Oculosystemic pneumocystosis in 2 sibling Chihuahuas.Journal of veterinary internal medicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Lynelle R JohnsonDepartment of Medicine and Epidemiology, University of California-Davis, Davis, California, USA.ORCID https://orcid.org/0000-0002-5331-5626
Sean E HulseboschDepartment of Medicine and Epidemiology, University of California-Davis, Davis, California, USA.ORCID https://orcid.org/0000-0003-0684-0871
Austin K ViallDepartment of Pathology, Microbiology & Immunology, University of California-Davis, Davis, California, USA.
Patrizia DanesiParasitology, Mycology and Medical Enthomology, Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, Italy.
Kevin D WoolardDepartment of Pathology, Microbiology & Immunology, University of California-Davis, Davis, California, USA.
Sarah E CookComparative Pathology Laboratory, University of California-Davis, Davis, California, USA.
David J MaggsDepartment of Surgical and Radiological Sciences, University of California-Davis, Davis, California, USA.
Brian C LeonardDepartment of Surgical and Radiological Sciences, University of California-Davis, Davis, California, USA.
University of California, Davis · USIstituto Zooprofilattico Sperimentale delle Venezie · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sibling female and male Chihuahuas were evaluated for a 9-month history of tachypnea that failed to respond to fenbendazole, doxycycline, amoxicillin-clavulanate, and prednisone. Physical examination identified tachypnea, hyperpnea, and harsh bronchovesicular lung sounds. Fundic examination disclosed diffuse chorioretinitis, manifested as multifocal chorioretinal granulomas in the female dog and occasional chorioretinal scars in the male dog. Thoracic radiographs indicated moderate to severe interstitial to broncho-interstitial infiltrates in both dogs. Serum and urine antigen and antibody testing in the female dog failed to identify infectious agents, but cytologic assessment of hepatic lymph node, liver, and splenic aspirates identified Pneumocystis trophozoites. Infection was confirmed in both dogs by 28S rRNA PCR sequencing from multiple tissue samples. The female dog responded well to trimethoprim-sulfamethoxazole, but the male dog was euthanized because of liver failure, presumably related to antimicrobial treatment.

Indexed as

Anti-Infective AgentsDog DiseasesPneumonia, PneumocystisAnimalsDogsFemaleHumansMalePrednisoneSiblingsTachypneaAnti-Infective AgentsPrednisonefundic examinationinfectious diseaseophthalmology

Identifiers

PMID37134072
PMCPMC10229366
OpenAlexW4367835379

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.