ArticleBrain topography2023
Activation of Cerebellum, Basal Ganglia and Thalamus During Observation and Execution of Mouth, hand, and foot Actions.
Article in Brain topography, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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15 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Combined repetitive transcranial magnetic stimulation and mirror therapy for upper limb rehabilitation in stroke survivors: A systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Pooled it
- Innovative upper extremity rehabilitation methods in stroke patients: a comparison of robotic rehabilitation and action observation therapy-a randomized trial.Frontiers in neurologyTrial
- Neural mechanisms of awareness of action.PNAS nexus · 2026Article
- Structural brain lesions and action observation therapy outcomes in unilateral cerebral palsy: an exploratory study.Frontiers in systems neuroscience · 2026Article
- What Else Is Happening to the Mirror Neurons?-A Bibliometric Analysis of Mirror Neuron Research Trends and Future Directions (1996-2024).Brain and behavior · 2025Article
- Exploring imitation of within hand prehensile object manipulation using fMRI and graph theory analysis.Scientific reports · 2025Article
- Bilateral force control and coordination patterns across upper and lower limbs.EXCLI journal · 2025Article
- The Role of Mirror Therapy in the Rehabilitation of the Upper Limb's Motor Deficits After Stroke: Narrative Review.Journal of clinical medicine · 2024Review
- Sensorimotor regulation of facial expression - An untouched frontier.Neuroscience and biobehavioral reviews · 2024Review
- Simultaneous cortical, subcortical, and brainstem mapping of sensory activation.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Simultaneous cortical, subcortical, and brainstem mapping of sensory activation.bioRxiv : the preprint server for biology · 2024Article
- Denoising task-correlated head motion from motor-task fMRI data with multi-echo ICA.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Brain activation during processing of mouth actions in patients with disorders of consciousness.Brain communications · 2024Article
- Action Observation and Motor Imagery as a Treatment in Patients with Parkinson's Disease.Journal of Parkinson's disease · 2024Review
- Denoising task-correlated head motion from motor-task fMRI data with multi-echo ICA.bioRxiv : the preprint server for biology · 2023Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Humans and monkey studies showed that specific sectors of cerebellum and basal ganglia activate not only during execution but also during observation of hand actions. However, it is unknown whether, and how, these structures are engaged during the observation of actions performed by effectors different from the hand. To address this issue, in the present fMRI study, healthy human participants were required to execute or to observe grasping acts performed with different effectors, namely mouth, hand, and foot. As control, participants executed and observed simple movements performed with the same effectors. The results show that: (1) execution of goal-directed actions elicited somatotopically organized activations not only in the cerebral cortex but also in the cerebellum, basal ganglia, and thalamus; (2) action observation evoked cortical, cerebellar and subcortical activations, lacking a clear somatotopic organization; (3) in the territories displaying shared activations between execution and observation, a rough somatotopy could be revealed in both cortical, cerebellar and subcortical structures. The present study confirms previous findings that action observation, beyond the cerebral cortex, also activates specific sectors of cerebellum and subcortical structures and it shows, for the first time, that these latter are engaged not only during hand actions observation but also during the observation of mouth and foot actions. We suggest that each of the activated structures processes specific aspects of the observed action, such as performing internal simulation (cerebellum) or recruiting/inhibiting the overt execution of the observed action (basal ganglia and sensory-motor thalamus).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.