Evidence map›Paper›PMID 37133615›Full record

ArticleLasers in medical science2023

Porphin e6 complex loaded with gold nanorod mesoporous silica enhances photodynamic therapy in ovarian cancer cells in vitro.

Qian Sun, Yuping Suo, Haoxuan Lv, Qian Wang, Hanzhen Yin

Abstract read
PubMed Publisher
In one paragraph

Article in Lasers in medical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Qian SunDepartment of Physiology, School of Basic Medicine, Shanxi Medical University, Taiyuan, 030001, Shanxi, China.
Yuping SuoDepartment of Gynaecology and Obstetrics, Shanxi Provincial People's Hospital, Taiyuan, 030012, Shanxi, China. ypsuo@sxmu.edu.cn.ORCID http://orcid.org/0000-0003-1776-4843
Haoxuan LvFifth Clinical Medical College of Shanxi Medical University, Taiyuan, 030012, Shanxi, China.
Qian WangFifth Clinical Medical College of Shanxi Medical University, Taiyuan, 030012, Shanxi, China.
Hanzhen YinCore Laboratory, Shanxi Provincial People's Hospital (Fifth Hospital) of Shanxi Medical University, Taiyuan, 030012, China.

Funding

National Natural Science Foundation of China 61775128National Natural Science Foundation of China 61975105
6 · The paper itself

Abstract

A growing amount of experimental evidence has proven that the application of gold nanorods (AuNRs) in photodynamic therapy (PDT) can significantly enhance its therapeutic efficacy. The aim of this study was to establish a protocol for investigating the effect of gold nanorods loaded with the photosensitizer chlorin e6 (Ce6) on photodynamic therapy in the OVCAR3 human ovarian cancer cell line in vitro and to determine whether the PDT effect was different from that of Ce6 alone. OVCAR3 cells were randomly divided into three groups: the control group, Ce6-PDT group, and AuNRs@SiO

Indexed as

ChlorophyllidesNanotubesOvarian NeoplasmsPhotochemotherapyPorphyrinsApoptosisCaspase 3Caspase 9Cell Line, TumorFemaleGoldHumansPhotosensitizing AgentsPoly(ADP-ribose) Polymerase InhibitorsReactive Oxygen SpeciesSilicon DioxideCaspase 3Caspase 9ChlorophyllidesGoldPhotosensitizing AgentsPoly(ADP-ribose) Polymerase InhibitorsporphinePorphyrinsReactive Oxygen SpeciesSilicon DioxideApoptosisCe6Gold nanorodsOvarian cancerPhotodynamic therapy

Identifiers

PMID37133615

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.