Evidence map›Paper›PMID 37133559›Full record

ArticlePsychopharmacology2023

Disentangling between- and within-person alcohol and expectancy effects on acute alcohol craving.

Jack T Waddell, Scott E King, William R Corbin

Open access · greenAbstract read
In one paragraph

Article in Psychopharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jack T WaddellDepartment of Psychology, Arizona State University, 900 S McAllister, Tempe, AZ, 85287-1104, USA. Jtwaddell@asu.edu.ORCID http://orcid.org/0000-0001-8406-6557
Scott E KingDepartment of Psychology, Arizona State University, 900 S McAllister, Tempe, AZ, 85287-1104, USA.
William R CorbinDepartment of Psychology, Arizona State University, 900 S McAllister, Tempe, AZ, 85287-1104, USA.
Arizona State University · US

Funding

Contextual Influences on Alcohol Response and its Relation to Drinking OutcomesR01AA021148 · NIAAA · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI CORBIN, WILLIAM R · 2013 to 2017
$1.5M
Between- and Within-Person Effects of Alcohol and Cannabis Co-Use on Subjective Alcohol Response and Problem DrinkingF31AA030167 · NIAAA · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI WADDELL, JACK T · 2022 to 2023
$68k
NIAAA NIH HHS F31 AA030167NIAAA NIH HHS F31-AA030167NIAAA NIH HHS R01 AA021148NIAAA NIH HHS R01-AA021148
6 · The paper itself

Abstract

objectiveAlcohol craving is a predictor of continued drinking and a diagnostic criterion for alcohol use disorder. Rewarding subjective effects potentiate craving, but it remains unclear if relations are expectancy-driven vs. alcohol-induced. In addition, it remains unclear if relations operate solely at the person level, or if there is also within-person dynamic change.

methodsParticipants (N = 448) come from a placebo-controlled alcohol administration study. Participants in the alcohol condition reported subjective effects and alcohol craving on ascending (BAC = .068), peak (BAC = .079), and descending (BAC = .066) BAC limbs. Participants in the placebo condition were yoked to alcohol condition participants. Multilevel models tested whether (1) within-person deviations in subjective effects predicted within-person deviations in craving, (2) between-person levels of subjective effects predicted between-person levels of craving, and (3) effects were dependent upon experimental condition.

resultsAt the within-person level, increases in high arousal positive/stimulant effects were associated with within-person increases in alcohol craving, regardless of experimental condition. At the between-person level, interactions were observed between high arousal positive/stimulant (and low arousal positive/relaxing) effects and condition. Probing suggested that the association between person-level high arousal positive/stimulant effects and craving was statistically significant in the alcohol but not the placebo condition. Conversely, the association between person-level low arousal positive/relaxing effects and craving was positive and statistically significant in the placebo but negative in the alcohol condition.

conclusionsFindings suggest expectancy-like relations among high arousal positive/stimulant effects and craving within-person. However, alcohol-induced positive reinforcement (i.e., stimulation) facilitated heightened person-level craving, whereas expectancy-like negative reinforcement (i.e., relaxation) attenuated person-level craving.

Indexed as

AlcoholismAlcohol-Related DisordersAlcohol DrinkingCravingEthanolHumansReinforcement, PsychologyEthanolAlcohol cravingAlcohol expectanciesPlaceboSubjective response

Identifiers

PMID37133559
PMCPMC10290517
OpenAlexW4367833825

What OpenQuestion holds

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LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.