ArticleSocial psychiatry and psychiatric epidemiology2023
Predictors of alcohol and substance use among people with post-traumatic stress disorder (PTSD): findings from the NESARC-III study.
Article in Social psychiatry and psychiatric epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- Colors of the mind: a meta-analysis of creative arts therapy as an approach for post-traumatic stress disorder intervention.BMC psychology · 2025Pooled it
- Factors impacting prazosin efficacy for nightmares and insomnia in PTSD patients - a systematic review and meta-regression analysis.Progress in neuro-psychopharmacology & biological psychiatry · 2025Pooled it
- Advancing models of PTSD-AUD comorbidity: protocol for a multimethod framework using genetics and ecological momentary assessment.European journal of psychotraumatology · 2026Article
- Single prolonged stress in mice: interactions between alcohol drinking, negative affect, and fear learning.Psychopharmacology · 2026Article
- Integrating Physical Health Dimensions in Middle-Aged and Older Adults to Predict Drug Misuse and Relapse Through a Comprehensive Needs Model: Protocol for a Mixed Methods Study.JMIR research protocols · 2026Article
- Role of peer support in mitigating PTSD and suicide risk among firefighters experiencing colleagues' death.European journal of psychotraumatology · 2025Article
- Exposure to traumatic events, PTSD, and alcohol use: A comparative study in Japan by type of traumatic event and gender.PCN reports : psychiatry and clinical neurosciences · 2025Article
- Insomnia and Mental Health Outcomes After Catastrophic Disasters: A Cross-Sectional Study Examining the Long-Term Effects of the Beirut Port Explosion.Neuropsychiatric disease and treatment · 2025Article
- Trauma, Stress, and Mental Health Outcomes.Journal of psychiatry and psychiatric disorders · 2025Article
- The role of recurrent trauma on post-traumatic stress disorder symptoms and substance use among trauma exposed youth.Psychiatry research · 2024Article
- The Role of Functional Health Literacy in terms of Harmful Alcohol Use in Adults with Probable Posttraumatic Stress Disorder and Alcohol Use Disorder.Research square · 2024Article
- PTSD, dysregulation profile and substance use: exploring differences in a sample of adolescents in an outpatient clinic.Frontiers in child and adolescent psychiatry · 2024Article
- The Role of Functional Health Literacy in Terms of Hazardous Alcohol Use in Adults with Probable Posttraumatic Stress Disorder and Alcohol Use Disorder.Journal of dual diagnosisArticle
- Latent Classes of Adolescent Trauma Exposure, Posttraumatic Stress Disorder Symptoms, and Substance Use Predict Clinical Diagnoses at 12-Month Follow-Up.Chronic stress (Thousand Oaks, Calif.)Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe self-medication hypothesis suggests people may develop Alcohol Use Disorder (AUD) or Non-Alcohol Substance Use Disorder (NA-SUD) following PTSD as a maladaptive way of coping with PTSD symptoms. Given that an accumulation of trauma experiences and interpersonal trauma increase the likelihood and severity of PTSD, we sought to determine whether the number and type of traumas additionally predict AUD and NA-SUD following PTSD.
methodsWe analysed data from 36,309 adult participants in the National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III) study (M = 45.63 years, SD = 17.53, 56.3% female) who were administered semi-structured diagnostic interviews of trauma exposure and PTSD, AUD and NA-SUD symptoms.
resultsIndividuals with PTSD were more likely to have an AUD or NA-SUD than those without PTSD. Endorsement of a greater number of traumas was associated with greater odds of having PTSD, AUD, or NA-SUD. Experience of interpersonal trauma was related to greater odds of having PTSD and subsequent AUD or NA-SUD than not experiencing interpersonal trauma. Multiple experiences of interpersonal trauma compared to one interpersonal trauma exposure also increased the odds of having PTSD followed by AUD or NA-SUD.
conclusionsInterpersonal trauma and multiple experiences of interpersonal trauma may result in individuals turning to alcohol and substances as a way to alleviate intolerable PTSD symptomology, aligning with the self-medication hypothesis. Our findings highlight the importance of ensuring services and support for interpersonal trauma survivors and for those who have experienced multiple traumas given their increased for unfavourable outcomes.
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