Evidence map›Paper›PMID 37133374›Full record

ArticleJournal of virology2023

Coronavirus Porcine Epidemic Diarrhea Virus Utilizes Chemokine Interleukin-8 to Facilitate Viral Replication by Regulating Ca

Xuyang Guo, Yingtong Feng, Xiaojing Zhao, Shuang Qiao, Zhiqian Ma, Zhiwei Li, Haixue Zheng, Shuqi Xiao

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 16 citations in OpenAlex.

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  11. Normal butanol fraction ofFrontiers in veterinary science · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Xuyang Guo *College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Yingtong Feng *College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Xiaojing ZhaoCollege of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Shuang QiaoCollege of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Zhiqian MaState Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, China.
Zhiwei LiCollege of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Haixue ZhengState Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, China.ORCID 0000-0001-6850-1379
Shuqi XiaoCollege of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.ORCID 0000-0002-6468-2608
Northwest A&F University · CNLanzhou Veterinary Research Institute · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemokine production by epithelial cells is crucial for neutrophil recruitment to sites of inflammation during viral infection. However, the effect of chemokine on epithelia and how chemokine is involved in coronavirus infection remains to be fully understood. Here, we identified an inducible chemokine interleukin-8 (CXCL8/IL-8), which could promote coronavirus porcine epidemic diarrhea virus (PEDV) infection in African green monkey kidney epithelial cells (Vero) and Lilly Laboratories cell-porcine kidney 1 epithelial cells (LLC-PK1). IL-8 deletion restrained cytosolic calcium (Ca

Indexed as

CoronavirusCoronavirus InfectionsPorcine epidemic diarrhea virusSwine DiseasesAnimalsChemokinesChlorocebus aethiopsInterleukin-8SwineVero CellsVirus ReplicationChemokinesInterleukin-8calcium signalinginfectioninterleukin-8porcine epidemic diarrhea virustherapy

Identifiers

PMID37133374
PMCPMC10231212
OpenAlexW4367834268

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.