Evidence map›Paper›PMID 37132645›Full record

ArticlePsychological medicine2023

Life expectancy, mortality risks and cause of death in patients with serious mental illness in South East London: a comparison between 2008-2012 and 2013-2017.

Chi-Kang Chang, Edward Chesney, Wei-Nung Teng, Sam Hollandt, Megan Pritchard, Hitesh Shetty, Robert Stewart, Philip McGuire, Rashmi Patel

Abstract read
In one paragraph

Article in Psychological medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chi-Kang ChangKing's College London, Institute of Psychiatry, Psychology & Neuroscience, London, UK.ORCID 0000-0002-9776-7763
Edward ChesneyKing's College London, Institute of Psychiatry, Psychology & Neuroscience, London, UK.
Wei-Nung TengDepartment of Anaesthesiology, Taipei Veterans General Hospital and National Yang-Ming University, Taipei City, Taiwan.ORCID 0000-0002-9619-9848
Sam HollandtKing's College London, Institute of Psychiatry, Psychology & Neuroscience, London, UK.
Megan PritchardSouth London and Maudsley NHS Foundation Trust, London, UK.
Hitesh ShettySouth London and Maudsley NHS Foundation Trust, London, UK.
Robert StewartKing's College London, Institute of Psychiatry, Psychology & Neuroscience, London, UK.
Philip McGuireKing's College London, Institute of Psychiatry, Psychology & Neuroscience, London, UK.
Rashmi PatelKing's College London, Institute of Psychiatry, Psychology & Neuroscience, London, UK.

Funding

Department of HealthMedical Research Council MR/S003118/1Medical Research Council MR/T045302/1Medical Research Council MR/V049879/1
6 · The paper itself

Abstract

backgroundPeople with serious mental illness (SMI) have a significantly shorter life expectancy than the general population. This study investigates whether the mortality rate in this group has changed over the last decade.

methodsUsing Clinical Record Interactive Search software, we extracted data from a large electronic database of patients in South East London. All patients with schizophrenia, schizoaffective disorder or bipolar disorder from 2008 to 2012 and/or 2013 to 2017 were included. Estimates of life expectancy at birth, standardised mortality ratios and causes of death were obtained for each cohort according to diagnosis and gender. Comparisons were made between cohorts and with the general population using data obtained from the UK Office of National Statistics.

resultsIn total, 26 005 patients were included. In men, life expectancy was greater in 2013-2017 (64.9 years; 95% CI 63.6-66.3) than in 2008-2012 (63.2 years; 95% CI 61.5-64.9). Similarly, in women, life expectancy was greater in 2013-2017 (69.1 years; 95% CI 67.5-70.7) than in 2008-2012 (68.1 years; 95% CI 66.2-69.9). The difference with general population life expectancy fell by 0.9 years between cohorts in men, and 0.5 years in women. In the 2013-2017 cohorts, cancer accounted for a similar proportion of deaths as cardiovascular disease.

conclusionsRelative to the general population, life expectancy for people with SMI is still much worse, though it appears to be improving. The increased cancer-related mortality suggests that physical health monitoring should consider including cancer as well.

Indexed as

Bipolar DisorderNeoplasmsCause of DeathFemaleHumansInfant, NewbornLife ExpectancyLondonMaleMortalityBipolar disordercause of deathlife expectancymortalityschizophreniastandardised mortality ratio

Identifiers

PMID37132645
PMCPMC9975985

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.