Evidence map›Paper›PMID 37132223›Full record

ArticleOpen biology2023

HSD3B1 is an oxysterol 3β-hydroxysteroid dehydrogenase in human placenta.

Alison Dickson, Eylan Yutuc, Catherine A Thornton, James E Dunford, Udo Oppermann, Yuqin Wang, William J Griffiths

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Alison DicksonSwansea University Medical School, ILS1 Building, Singleton Park, Swansea SA2 8PP, UK.
Eylan YutucSwansea University Medical School, ILS1 Building, Singleton Park, Swansea SA2 8PP, UK.
Catherine A ThorntonSwansea University Medical School, ILS1 Building, Singleton Park, Swansea SA2 8PP, UK.
James E DunfordCentre for Translational Myeloma Research, NIHR Biomedical Research Centre, Botnar Research Centre, University of Oxford, Oxford OX3 7LD, UK.ORCID 0000-0002-9932-4042
Udo OppermannCentre for Translational Myeloma Research, NIHR Biomedical Research Centre, Botnar Research Centre, University of Oxford, Oxford OX3 7LD, UK.
Yuqin WangSwansea University Medical School, ILS1 Building, Singleton Park, Swansea SA2 8PP, UK.
William J GriffithsSwansea University Medical School, ILS1 Building, Singleton Park, Swansea SA2 8PP, UK.ORCID 0000-0002-4129-6616
Swansea University · GBUniversity of Oxford · GB

Funding

Biotechnology and Biological Sciences Research Council BB/I001735/1Biotechnology and Biological Sciences Research Council BB/L001942/1Biotechnology and Biological Sciences Research Council BB/N015932/1Biotechnology and Biological Sciences Research Council BB/S019588/1
6 · The paper itself

Abstract

Most biologically active oxysterols have a 3β-hydroxy-5-ene function in the ring system with an additional site of oxidation at C-7 or on the side-chain. In blood plasma oxysterols with a 7α-hydroxy group are also observed with the alternative 3-oxo-4-ene function in the ring system formed by ubiquitously expressed 3β-hydroxy-Δ

Indexed as

OxysterolsFemaleHumansIsomerasesMultienzyme ComplexesPlacentaPregnancyProgesterone ReductaseSteroid IsomerasesSteroids3 beta-hydroxysteroid oxidoreductase-delta(5) 3-ketosteroid isomeraseIsomerasesMultienzyme ComplexesOxysterolsProgesterone ReductaseSteroid IsomerasesSteroidsbile acidHSD3B1mass spectrometryoxysterolplacentapregnancy

Identifiers

PMID37132223
PMCPMC10154939
OpenAlexW4367835196

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.