Evidence map›Paper›PMID 37132126›Full record

ArticleBJOG : an international journal of obstetrics and gynaecology2023

Care after premenopausal risk-reducing salpingo-oophorectomy in high-risk women: Scoping review and international consensus recommendations.

Denise R Nebgen, Susan M Domchek, Joanne Kotsopoulos, Joanne A de Hullu, Emma J Crosbie, Vincent Singh Paramanandam, Monique M A Brood-van Zanten, Barbara M Norquist, Theresa Guise, Serge Rozenberg and 17 more

Open access · hybridAbstract readScoping ReviewConsensus Statement
In one paragraph

Article in BJOG : an international journal of obstetrics and gynaecology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
9.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 31 citations in OpenAlex.

  1. Menopausal hormone therapy and comprehensive postmenopausal care in gynecologic cancer survivors: A position paper from the FIGO Committee on Women at Menopausal Age.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
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  10. Unilateral Oophorectomy and Age at Natural Menopause: A Longitudinal Community-Based Cohort Study.BJOG : an international journal of obstetrics and gynaecology · 2025
    Article
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  12. Menopause in gynecologic cancer survivors: evidence for decision-making.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 20 institutions in 11 countries.

Denise R NebgenDepartment of Gynecologic Oncology and Reproductive Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.ORCID 0000-0003-0576-3368
Susan M DomchekBasser Center for BRCA, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-5914-7272
Joanne KotsopoulosWomen's College Research Institute, Women's College Hospital, University of Toronto, Toronto, Ontario, Canada.
Joanne A de HulluDepartment of Obstetrics and Gynaecology, Radboud University Medical Centre, Nijmegen, The Netherlands.
Emma J CrosbieDivision of Cancer Sciences, University of Manchester, St Mary's Hospital, Manchester, UK.ORCID 0000-0003-0284-8630
Vincent Singh ParamanandamDepartment of Obstetrics and Gynaecology, The Royal Women's Hospital, The University of Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0002-9976-9172
Monique M A Brood-van ZantenDepartment of Gynecology, The Netherlands Cancer Institute, Amsterdam University Medical Centres, Amsterdam, The Netherlands.ORCID 0000-0002-2275-9558
Barbara M NorquistDepartment of Obstetrics and Gynecology, University of Washington, Seattle, Washington, USA.ORCID 0000-0001-5992-7845
Theresa GuiseDepartment of Endocrine Neoplasia and Hormone Disorders, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Serge RozenbergDepartment of Obstetrics and Gynaecology, Universite Libre de Bruxelles, Brussels, Belgium.
Allison W KurianStanford Cancer Institute, Stanford University School of Medicine, Stanford, California, USA.ORCID 0000-0002-6175-9470
Holly J PedersonCase Comprehensive Cancer Center/University Hospitals Seidman Cancer Center, Cleveland Clinic Taussig Cancer Institute, Cleveland, Ohio, USA.
Nese YukselFaculty of Pharmacy and Pharmaceutical Sciences, College of Health Sciences, University of Alberta, Edmonton, Alberta, Canada.ORCID 0000-0002-5154-7490
Rachel Michaelson-CohenDepartment of Gynaecology and Medical Genetics Institute, Hebrew University Faculty of Medicine, Shaare Zedek Medical Centre, Jerusalem, Israel.ORCID 0000-0002-2543-664X
Sharon L BoberDana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0002-2793-2620
Agnaldo Lopes da Silva FilhoDepartamento de Ginecologia e Obstetricia da UFMG, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Nora JohansenDepartment of Gynaecology and Obstetrics, Sørlandet Hospital HF Arendal, Arendal, Norway.ORCID 0000-0002-7670-400X
F GuidozziDeparment of Obstetrics and Gynaecology, University of Witwatersrand, Johanesburg, South Africa.ORCID 0000-0001-6947-4210
D Gareth EvansUniversity of Manchester, Prevent Breast Cancer Centre, Manchester, UK.ORCID 0000-0002-8482-5784
Usha MenonMRC Clinical Trials Unit, Institute of Clinical Trials and Methodology, University College London, London, UK.ORCID 0000-0003-3708-1732
Sheryl A KingsbergUniversity Hospitals Cleveland Medical Center, Case Western University School of Medicine, Cleveland, Ohio, USA.ORCID 0000-0001-6350-1505
C Bethan PowellKaiser Permanente Northern California, Hereditary Cancer Program, San Francisco, California, USA.ORCID 0000-0002-3599-1655
Giovanni GrandiDepartment of Medical and Surgical Sciences for Mother, Child and Adult, University of Modena and Reggio Emilia, Modena, Italy.ORCID 0000-0002-3567-3278
Claudia MarchettiDepartment of Women's and Children's Health, Fondazione Policlinico Universitario A. Gemelli, IRCCS-Catholic University Sacred Heart, Rome, Italy.ORCID 0000-0001-7098-8956
Michelle JacobsonWomen's College Hospital and Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.
Donal J BrennanUCD Gynaecological Oncology Group, UCD School of Medicine, Mater University Hospital, Dublin, Ireland.
Martha HickeyDepartment of Obstetrics and Gynaecology, Research Precinct, Level 7, The Royal Women's Hospital, University of Melbourne, Parkville, Victoria, Australia.ORCID 0000-0002-3941-082X
Royal Women's Hospital · AUThe University of Texas MD Anderson Cancer Center · USUniversity of Manchester · GBCleveland Clinic · USHarvard University · USKaiser Permanente · USMater Private Hospital · AUMount Sinai Hospital · CAMRC Clinical Trials Unit at UCL · GBRadboud University Nijmegen · NLShaare Zedek Medical Center · ILSørlandet Hospital Arendal · NOStanford University · USThe Netherlands Cancer Institute · NLUniversidade Federal de Minas Gerais · BRUniversité Libre de Bruxelles · BEUniversity Hospitals of Cleveland · USUniversity of Alberta · CAUniversity of Modena and Reggio Emilia · ITUniversity of Pennsylvania · US

Funding

Department of Health IS-BRC-1215-20007Medical Research Council MC_UU_00004/01
6 · The paper itself

Abstract

Women at high inherited risk of ovarian cancer are offered risk-reducing salpingo-oophorectomy (RRSO) from age 35 to 45 years. Although potentially life-saving, RRSO may induce symptoms that negatively affect quality of life and impair long-term health. Clinical care following RRSO is often suboptimal. This scoping review describes how RRSO affects short- and long-term health and provides evidence-based international consensus recommendations for care from preoperative counselling to long-term disease prevention. This includes the efficacy and safety of hormonal and non-hormonal treatments for vasomotor symptoms, sleep disturbance and sexual dysfunction and effective approaches to prevent bone and cardiovascular disease.

Indexed as

Ovarian NeoplasmsSalpingo-oophorectomyAdultFemaleGenetic Predisposition to DiseaseHumansMiddle AgedOvariectomyPremenopauseQuality of LifeBRCA1BRCA2early menopausehormone replacement therapyhot flushesovarian cancerrisk-reducing salpingo-oophorectomysexual functionsurgical menopause

Identifiers

PMID37132126
PMCPMC7617419
OpenAlexW4367834628

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.