Evidence map›Paper›PMID 37132062›Full record

Observational studyAddiction (Abingdon, England)2023

All-cause and cause-specific mortality in individuals with an alcohol-related emergency or hospital inpatient presentation: A retrospective data linkage cohort study.

Janni Leung, Vivian Chiu, Nicola Man, Wing See Yuen, Timothy Dobbins, Adrian Dunlop, Natasa Gisev, Wayne Hall, Sarah Larney, Sallie-Anne Pearson and 2 more

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in Addiction (Abingdon, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Janni LeungNational Drug and Alcohol Research Centre, UNSW Sydney, Sydney, NSW, Australia.ORCID 0000-0001-5816-2959
Vivian ChiuNational Drug and Alcohol Research Centre, UNSW Sydney, Sydney, NSW, Australia.ORCID 0000-0002-8729-3330
Nicola ManNational Drug and Alcohol Research Centre, UNSW Sydney, Sydney, NSW, Australia.ORCID 0000-0003-2224-9301
Wing See YuenNational Drug and Alcohol Research Centre, UNSW Sydney, Sydney, NSW, Australia.ORCID 0000-0002-2791-6858
Timothy DobbinsSchool of Population Health, UNSW Sydney, Sydney, NSW, Australia.ORCID 0000-0003-1841-9056
Adrian DunlopHunter New England Health, New South Wales Government, Newcastle, NSW, Australia.
Natasa GisevNational Drug and Alcohol Research Centre, UNSW Sydney, Sydney, NSW, Australia.
Wayne HallFaculty of Health and Behavioural Sciences, University of Queensland, Brisbane, QLD, Australia.ORCID 0000-0003-1984-0096
Sarah LarneyNational Drug and Alcohol Research Centre, UNSW Sydney, Sydney, NSW, Australia.ORCID 0000-0002-5602-4963
Sallie-Anne PearsonMedicines Policy Research Unit, Centre for Big Data Research in Health, UNSW Sydney, Sydney, NSW, Australia.
Louisa DegenhardtNational Drug and Alcohol Research Centre, UNSW Sydney, Sydney, NSW, Australia.ORCID 0000-0002-8513-2218
Amy PeacockNational Drug and Alcohol Research Centre, UNSW Sydney, Sydney, NSW, Australia.ORCID 0000-0002-5705-2026
UNSW Sydney · AUThe University of Queensland · AUGovernment of New South Wales · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsAlcohol consumption is a leading risk factor for premature mortality globally, but there are limited studies of broader cohorts of people presenting with alcohol-related problems outside of alcohol treatment services. We used linked health administrative data to estimate all-cause and cause-specific mortality among individuals who had an alcohol-related hospital inpatient or emergency department presentation.

designObservational study using data from the Data linkage Alcohol Cohort Study (DACS), a state-wide retrospective cohort of individuals with an alcohol-related hospital inpatient or emergency department presentation.

settingHospital inpatient or emergency department presentation in New South Wales, Australia, between 2005 and 2014.

participantsParticipants comprised 188 770 individuals aged 12 and above, 66% males, median age 39 years at index presentation. MEASUREMENTS: All-cause mortality was estimated up to 2015 and cause-specific mortality (by those attributable to alcohol and by specific cause of death groups) up to 2013 due to data availability. Age-specific and age-sex-specific crude mortality rates (CMRs) were estimated, and standardized mortality ratios (SMRs) were calculated using sex and age-specific deaths rates from the NSW population.

findingsThere were 188 770 individuals in the cohort (1 079 249 person-years of observation); 27 855 deaths were recorded (14.8% of the cohort), with a CMR of 25.8 [95% confidence interval (CI) = 25.5, 26.1] per 1000 person-years and SMR of 6.2 (95% CI = 5.4, 7.2). Mortality in the cohort was consistently higher than the general population in all adult age groups and in both sexes. The greatest excess mortality was from mental and behavioural disorders due to alcohol use (SMR = 46.7, 95% CI = 41.4, 52.7), liver cirrhosis (SMR = 39.0, 95% CI = 35.5, 42.9), viral hepatitis (SMR = 29.4, 95% CI = 24.6, 35.2), pancreatic diseases (SMR = 23.8, 95% CI = 17.9, 31.5) and liver cancer (SMR = 18.3, 95% CI = 14.8, 22.5). There were distinct differences between the sexes in causes of excess mortality (all causes fully attributable to alcohol female versus male risk ratio = 2.5 (95% CI = 2.0, 3.1).

conclusionsIn New South Wales, Australia, people who came in contact with an emergency department or hospital for an alcohol-related presentation between 2005 and 2014 were at higher risk of mortality than the general New South Wales population during the same period.

Indexed as

Alcohol-Related DisordersAdultCause of DeathCohort StudiesFemaleHumansInformation Storage and RetrievalMaleRetrospective StudiesAlcoholemergency departmenthospitalizationinjuryintoxicationlinkageliver diseasemortality

Identifiers

PMID37132062
PMCPMC10952273
OpenAlexW4367833933

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.