Evidence map›Paper›PMID 37132048›Full record

ArticleChild development

Association of Gestational Diabetes Mellitus and Perinatal Maternal Depression with Early Childhood Behavioral Problems: An Environmental Influences on Child Health Outcomes (ECHO) Study.

Lauren C Shuffrey, Santiago Morales, Melanie H Jacobson, Michelle Bosquet Enlow, Akhgar Ghassabian, Amy E Margolis, Maristella Lucchini, Kecia N Carroll, Rosa M Crum, Dana Dabelea and 15 more

Open access · bronzeAbstract read
In one paragraph

Article in Child development. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 14 institutions in 1 country.

Lauren C ShuffreyDepartment of Psychiatry, Columbia University Vagelos College of Physicians and Surgeons, New York, New York, USA.ORCID 0000-0003-3631-5971
Santiago MoralesDepartment of Psychology, University of Southern California, Los Angeles, California, USA.
Melanie H JacobsonDepartment of Pediatrics, Division of Environmental Pediatrics, New York University School of Medicine, New York, New York, USA.
Michelle Bosquet EnlowDepartment of Psychiatry and Behavioral Sciences, Boston Children's Hospital, Boston, Massachusetts, USA.
Akhgar GhassabianDepartment of Pediatrics, New York University School of Medicine, New York, New York, USA.
Amy E MargolisDepartment of Psychiatry, Columbia University Vagelos College of Physicians and Surgeons, New York, New York, USA.ORCID 0000-0002-3334-6783
Maristella LucchiniDepartment of Psychiatry, Columbia University Vagelos College of Physicians and Surgeons, New York, New York, USA.
Kecia N CarrollIcahn School of Medicine at Mount Sinai, New York, New York, USA.
Rosa M CrumDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Dana DabeleaLifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Arielle DeutschAvera Research Institute, Sioux Falls, South Dakota, USA.
William P FiferDepartment of Psychiatry, Columbia University Vagelos College of Physicians and Surgeons, New York, New York, USA.
Brandon GoldsonIcahn School of Medicine at Mount Sinai, New York, New York, USA.
Christine W HockettAvera Research Institute, Sioux Falls, South Dakota, USA.
W Alex MasonDepartment of Preventive Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Lisette T JacobsonDepartment of Population Health, Department of Obstetrics & Gynecology, University of Kansas School of Medicine, Wichita, Kansas, USA.
Thomas G O'ConnorDepartments of Psychiatry, Psychology, Neuroscience, and Obstetrics and Gynecology, University of Rochester, Rochester, New York, USA.ORCID 0000-0002-8590-5057
Nicolò PiniDepartment of Psychiatry, Columbia University Vagelos College of Physicians and Surgeons, New York, New York, USA.
Yael RayportDepartment of Psychiatry, Columbia University Vagelos College of Physicians and Surgeons, New York, New York, USA.
Ayesha SaniaDepartment of Psychiatry, Columbia University Vagelos College of Physicians and Surgeons, New York, New York, USA.
Leonardo TrasandeDepartment of Pediatrics, New York University Grossman School of Medicine, New York, New York, USA.
Rosalind J WrightIcahn School of Medicine at Mount Sinai, New York, New York, USA.
Seonjoo LeeMailman School of Public Health, Columbia University Vagelos College of Physicians and Surgeons, New York, New York, USA.
Catherine MonkDepartment of Psychiatry, Columbia University Vagelos College of Physicians and Surgeons, New York, New York, USA.
program collaborators for Environmental influences on Child Health Outcomes
Columbia University · USIcahn School of Medicine at Mount Sinai · USNew York University · USAvera Health · USBoston Children's Hospital · USColumbia University Irving Medical Center · USJohns Hopkins University · USNew York Psychoanalytic Society and Institute · USUniversity of Colorado Anschutz Medical Campus · USUniversity of Kansas · USUniversity of Rochester · USUniversity of South Dakota · USUniversity of Southern California · USUniversity of Tennessee Health Science Center · US

Funding

Project-005U2COD023375 · OD · DUKE UNIVERSITY · PI Linda S Adair, Phillip Brian Smith · 2016 to 2026
$215.9M
ECHODAC (Environmental Influences on Child Health Outcomes Data Analysis Center)U24OD023382 · OD · JOHNS HOPKINS UNIVERSITY · PI Diane J Catellier, LISA P JACOBSON · 2016 to 2026
$148.4M
The NYU Children’s Health & Environment Study: an ECHO CohortUH3OD023305 · OD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Akhgar Ghassabian, Leonardo Trasande · 2018 to 2026
$59.5M
Mount Sinai ECHO site for Perinatal Environment and Development StudiesUH3OD023337 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KECIA Nicole CARROLL, Robert O Wright · 2018 to 2026
$54.1M
The ECHO Measurement Core: A Framework and Resource for Assessing Environmental Exposure and Child HealthU24OD023319 · OD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Courtney K Blackwell, RICHARD GERSHON · 2016 to 2026
$43.7M
Prenatal and Early Childhood Pathways To Health:  An Integrated Model of Chemical and Social Exposures, Biological Mechanisms, and Sex-Specific Effects on Neurodevelopment and Respiratory OutcomesUH3OD023271 · OD · UNIVERSITY OF WASHINGTON · PI BUSH, NICOLE RENEE, KARR, CATHERINE J · 2018 to 2022
$37.3M
Environmental Influences on Childhood Outcomes in the Northern Plains Safe Passage Study CohortsUH3OD023279 · OD · AVERA MCKENNAN · PI Amy J Elliott, Christine W Hockett · 2018 to 2026
$31.7M
BREAKING THE CYCLE OF INTERGENERATIONAL DISADVANTAGE: NEURODEVELOPMENT AMONG PUERTO RICAN CHILDREN.UH3OD023328 · OD · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI CANINO, GLORISA J, DUARTE, CRISTIANE S. · 2018 to 2022
$18.3M
Pre- and Postnatal Exposure Periods for Child Health: Common Risks and Shared MechanismsUH3OD023349 · OD · UNIVERSITY OF ROCHESTER · PI Emily S Barrett, Richard Kermit Miller · 2018 to 2026
$15.9M
The Early Life Exposome and Childhood Health - The Colorado Healthy Start 3 Cohort StudyUH3OD023248 · OD · UNIVERSITY OF COLORADO DENVER · PI Traci Allison Bekelman, Dana Dabelea · 2018 to 2026
$14.8M
Gestational Diabetes Mellitus, Perinatal Depression, and Offspring Neurodevelopmental Phenotype - Diversity SupplementR00HD103910 · NICHD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SHUFFREY, LAUREN CHRISTINE · 2023 to 2025
$853k
Gestational Diabetes Mellitus, Perinatal Depression, and Offspring Neurodevelopmental PhenotypeK99HD103910 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHUFFREY, LAUREN CHRISTINE · 2021 to 2022
$262k
NICHD NIH HHS K99 HD103910NICHD NIH HHS L40 HD099886NICHD NIH HHS R00 HD103910NIH HHS U24 OD023319NIH HHS U24 OD023382NIH HHS U2C OD023375NIH HHS UH3 OD023248NIH HHS UH3 OD023271NIH HHS UH3 OD023279NIH HHS UH3 OD023305NIH HHS UH3 OD023328NIH HHS UH3 OD023337NIH HHS UH3 OD023349ODCDC CDC HHS UH3 OD023248ODCDC CDC HHS UH3 OD023271ODCDC CDC HHS UH3 OD023279ODCDC CDC HHS UH3 OD023305ODCDC CDC HHS UH3 OD023328ODCDC CDC HHS UH3 OD023337ODCDC CDC HHS UH3 OD023349
6 · The paper itself

Abstract

This study examined the association of gestational diabetes mellitus (GDM), prenatal, and postnatal maternal depressive symptoms with externalizing, internalizing, and autism spectrum problems on the Preschool Child Behavior Checklist in 2379 children aged 4.12 ± 0.60 (48% female; 47% White, 32% Black, 15% Mixed Race, 4% Asian, <2% American Indian/Alaskan Native, <2% Native Hawaiian; 23% Hispanic). Data were collected from the NIH Environmental influences on Child Health Outcomes (ECHO) Program from 2009-2021. GDM, prenatal, and postnatal maternal depressive symptoms were each associated with increased child externalizing and internalizing problems. GDM was associated with increased autism behaviors only among children exposed to perinatal maternal depressive symptoms above the median level. Stratified analyses revealed a relation between GDM and child outcomes in males only.

Indexed as

Depressive DisorderDiabetes, GestationalChild, PreschoolDepressionFemaleHumansMaleMothersOutcome Assessment, Health CarePregnancy

Identifiers

PMID37132048
PMCPMC10620104
OpenAlexW4367835123

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.