Evidence map›Paper›PMID 37132013›Full record

ArticleImmuno-oncology insights2022

Preclinical models for development of immune-oncology therapies.

Yufei Wang, Sarah E Shelton, Gabriella Kastrunes, David A Barbie, Gordon J Freeman, Wayne A Marasco

Abstract read
In one paragraph

Article in Immuno-oncology insights, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Translational 3DFrontiers in immunology · 2026
    Article
  5. Review
  6. Article
  7. Hematological toxicity of [EJNMMI radiopharmacy and chemistry · 2025
    Article
  8. Leveraging T cells for cancer immunotherapy.Immunity & inflammation · 2025
    Review
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yufei WangDepartment of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA and Harvard Medical School, Boston, MA 02115, USA.
Sarah E SheltonDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA and Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Gabriella KastrunesDepartment of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA.
David A BarbieHarvard Medical School, Boston, MA 02115, USA and Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
Gordon J FreemanHarvard Medical School, Boston, MA 02115, USA and Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA.
Wayne A MarascoDepartment of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA and Harvard Medical School, Boston, MA 02115, USA.

Funding

Treating the P13-Kinase/AKTP50CA101942 · NCI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI David McDermott · 2003 to 2026
$53.4M
Imaging Cancer Angiogenesis with Acoustic Angiography UltrasoundK00CA212227 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI SHELTON, SARAH ELIZABETH · 2018 to 2021
$392k
NCI NIH HHS K00 CA212227NCI NIH HHS P50 CA101942
6 · The paper itself

Abstract

Immunotherapy has demonstrated great success in clinical treatment, especially for cancer care. Here we review preclinical models, including cell lines, three dimensional (3D) cultures, and mouse models to support the need for tools enabling the development of novel immune-oncology (I-O) therapies. While

Identifiers

PMID37132013
PMCPMC10150782

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.