Evidence map›Paper›PMID 37131940›Full record

ArticleBulletin of the World Health Organization2023

Sales of antibiotics without a prescription in pharmacies, 2017 and 2021, China.

Jie Chen, Ying Xie, Yiting Sun, Ruichen Zang, Yuhao Sun, Lintao Dan, Xuanding Wang, Therese Hesketh

Abstract read
In one paragraph

Article in Bulletin of the World Health Organization, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Prescription-only medicine requests by clients: Insights from community pharmacies.Exploratory research in clinical and social pharmacy · 2026
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jie ChenCentre for Global Health, Zhejiang University School of Medicine, 866 Yuhangtang Road, Hangzhou310058, China.
Ying XieSchool of Health Policy and Management, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Yiting SunCentre for Global Health, Zhejiang University School of Medicine, 866 Yuhangtang Road, Hangzhou310058, China.
Ruichen ZangCentre for Global Health, Zhejiang University School of Medicine, 866 Yuhangtang Road, Hangzhou310058, China.
Yuhao SunCentre for Global Health, Zhejiang University School of Medicine, 866 Yuhangtang Road, Hangzhou310058, China.
Lintao DanCentre for Global Health, Zhejiang University School of Medicine, 866 Yuhangtang Road, Hangzhou310058, China.
Xuanding WangDepartment of Antimicrobial Stewardship, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Therese HeskethCentre for Global Health, Zhejiang University School of Medicine, 866 Yuhangtang Road, Hangzhou310058, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To measure sales of antibiotics without a prescription in pharmacies in China in 2017 and 2021, before and during the coronavirus disease 2019 (COVID-19) pandemic, and determine the factors associated with such sales. Methods: We conducted cross-sectional surveys using the simulated patient method in retail pharmacies in 13 provinces in eastern, central and western China in 2017 and 2021. At the pharmacies, the simulated patients (trained medical students) reported that they had mild respiratory tract symptoms and asked for treatment, using a three-stage process: (i) request some treatment; (ii) request antibiotics; (iii) request specific antibiotics. We used multivariable logistic regression analysis to determine factors associated with sale of antibiotics without a prescription. Findings: Of the pharmacies visited in 2017, 83.6% (925/1106) sold antibiotics without a prescription; this figure was 78.3% (853/1090) in 2021 ( Conclusion: Although laws became stricter between 2017 and 2021, antibiotic sales without a prescription were still common in pharmacies across China. Existing regulations need to be more strictly enforced, and pharmacy staff and the public should be made more aware of the risks of antibiotic misuse and dangers of antimicrobial resistance.

Indexed as

Anti-Bacterial AgentsPharmaciesChinaCommerceCOVID-19Cross-Sectional StudiesHumansPrescriptionsAnti-Bacterial Agents

Identifiers

PMID37131940
PMCPMC10140688

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.