Evidence map›Paper›PMID 37131824›Full record

ArticlemedRxiv : the preprint server for health sciences2023

Gut community structure as a risk factor for infection in

Jay Vornhagen, Krishna Rao, Michael A Bachman

Open access · greenAbstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Krishna Rao
Michael A Bachman
Michigan Medicine · USIndiana University School of Medicine

Funding

Integrated modeling of Klebsiella pneumoniae infections based on bacterial genotype, patient factors and colonization statusR01AI125307 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BACHMAN, MICHAEL ABBOTT · 2017 to 2021
$2.6M
Assessing Klebsiella pneumoniae invasion of the intact gut microbiomeR00AI153483 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI VORNHAGEN, JAY · 2023 to 2024
$494k
Assessing Klebsiella pneumoniae invasion of the intact gut microbiomeK99AI153483 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI VORNHAGEN, JAY · 2021 to 2022
$163k
NIAID NIH HHS K99 AI153483NIAID NIH HHS R00 AI153483NIAID NIH HHS R01 AI125307
6 · The paper itself

Abstract

The primary risk factor for infection with members of Importance: Colonization is generally the first step in pathogenesis for bacteria with pathogenic potential. This step provides a unique window for intervention since a given potential pathogen has yet to cause damage to its host. Moreover, intervention during the colonization stage may help alleviate the burden of therapy failure as antimicrobial resistance rises. Yet, to understand the therapeutic potential of interventions that target colonization, we must first understand the biology of colonization and if biomarkers at the colonization stage can be used to stratify infection risk. The bacterial genus

Identifiers

PMID37131824
PMCPMC10153327
OpenAlexW4366596261

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.