ArticlebioRxiv : the preprint server for biology2023
Pharmacological chaperones restore proteostasis of epilepsy-associated GABA
Ya-Juan Wang, Hailey Seibert, Lucie Y Ahn, Ashleigh E Schaffer, Ting-Wei Mu
Open access · greenAbstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 3 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
5 authors at 1 institution in 1 country.
Ya-Juan WangDepartment of Physiology and Biophysics, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.
Hailey SeibertDepartment of Biochemistry, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.
Lucie Y AhnDepartment of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.
Ashleigh E SchafferDepartment of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.
Ting-Wei MuDepartment of Physiology and Biophysics, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.
University School · US
Funding
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007250 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI HUANG, ALEX YEE-CHEN · 1985 to 2023
$33.4MMedical Scientist Training Program at Case Western Reserve UniversityT32GM152319 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI Heather Broihier, Alex Yee-Chen Huang · 2024 to 2026
$5.1MUnderstanding GABAA receptor protein folding and misfoldingR01NS105789 · NINDS · CASE WESTERN RESERVE UNIVERSITY · PI Tingwei Mu · 2018 to 2026
$3.9MDisease Mechanisms of Pontocerebellar Hypoplasia Type 10R01NS123524 · NINDS · CASE WESTERN RESERVE UNIVERSITY · PI SCHAFFER, ASHLEIGH E · 2021 to 2025
$2.6MAssembly Chaperone Complex for Membrane Proteins in the Endoplasmic ReticulumR01NS117176 · NINDS · CASE WESTERN RESERVE UNIVERSITY · PI MU, TINGWEI · 2020 to 2023
$1.6MFunctional Genomics Training Program (FGTP)T32GM135081 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI Thomas Louis LaFramboise, Helen C Miranda · 2020 to 2026
$1.3MNIGMS NIH HHS T32 GM007250NIGMS NIH HHS T32 GM135081NIGMS NIH HHS T32 GM152319NINDS NIH HHS R01 NS105789NINDS NIH HHS R01 NS117176NINDS NIH HHS R01 NS123524
6 · The paper itselfAbstract
Recent advances in genetic diagnosis identified variants in genes encoding GABA
Identifiers
PMID37131660
PMCPMC10153171
OpenAlexW4366595794
What OpenQuestion holds
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