Evidence map›Paper›PMID 37131603›Full record

ArticlemedRxiv : the preprint server for health sciences2023

Sleep Regularity and Mortality: A Prospective Analysis in the UK Biobank.

Lachlan Cribb, Ramon Sha, Stephanie Yiallourou, Natalie A Grima, Marina Cavuoto, Andree-Ann Baril, Matthew P Pase

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Lachlan CribbTurner Institute for Brain and Mental Health, Monash University, Melbourne Australia.
Ramon ShaTurner Institute for Brain and Mental Health, Monash University, Melbourne Australia.
Stephanie YiallourouTurner Institute for Brain and Mental Health, Monash University, Melbourne Australia.
Natalie A GrimaTurner Institute for Brain and Mental Health, Monash University, Melbourne Australia.
Marina CavuotoTurner Institute for Brain and Mental Health, Monash University, Melbourne Australia.
Andree-Ann BarilDouglas Mental Health University Institute, McGill University, Montreal, QC, Canada.
Matthew P PaseTurner Institute for Brain and Mental Health, Monash University, Melbourne Australia.
Monash University · AUDouglas Mental Health University Institute · CAHarvard University · USNational Ageing Research Institute · AU

Funding

Contributions of sleep to preclinical and clinical Alzheimer's diseaseR01AG062531 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI HIMALI, JAYANDRA JUNG, PASE, MATTHEW · 2020 to 2023
$3.1M
NIA NIH HHS R01 AG062531
6 · The paper itself

Abstract

Background: Irregular sleep-wake timing may cause circadian disruption leading to several chronic age-related diseases. We examined the relationship between sleep regularity and risk of all-cause, cardiovascular disease (CVD), and cancer mortality in 88,975 participants from the prospective UK Biobank cohort. Methods: The sleep regularity index (SRI) was calculated as the probability of an individual being in the same state (asleep or awake) at any two time points 24 hours apart, averaged over 7-days of accelerometry (range 0-100, with 100 being perfectly regular). The SRI was related to the risk of mortality in time-to-event models. Findings: The mean sample age was 62 years (SD, 8), 56% were women, and the median SRI was 60 (SD, 10). There were 3010 deaths during a mean follow-up of 7.1 years. Following adjustments for demographic and clinical variables, we identified a non-linear relationship between the SRI and all-cause mortality hazard ( Conclusions: Irregular sleep-wake patterns are associated with higher mortality risk. Funding: National Health and Medical Research Council of Australia (GTN2009264; GTN1158384), National Institute on Aging (AG062531), Alzheimer's Association (2018-AARG-591358), and the Banting Fellowship Program (#454104).

Identifiers

PMID37131603
PMCPMC10153326
OpenAlexW4366287799

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.