Evidence map›Paper›PMID 37131601›Full record

ArticlebioRxiv : the preprint server for biology2023

DNA-m6A calling and integrated long-read epigenetic and genetic analysis with fibertools.

Anupama Jha, Stephanie C Bohaczuk, Yizi Mao, Jane Ranchalis, Benjamin J Mallory, Alan T Min, Morgan O Hamm, Elliott Swanson, Danilo Dubocanin, Connor Finkbeiner and 5 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Anupama JhaDepartment of Genome Sciences, University of Washington, Seattle, WA, USA.ORCID 0000-0003-3029-2086
Stephanie C BohaczukDivision of Medical Genetics, University of Washington School of Medicine, Seattle, WA, USA.ORCID 0000-0001-8802-6579
Yizi MaoDivision of Medical Genetics, University of Washington School of Medicine, Seattle, WA, USA.ORCID 0000-0001-5743-6831
Jane RanchalisDivision of Medical Genetics, University of Washington School of Medicine, Seattle, WA, USA.
Benjamin J MalloryDepartment of Genome Sciences, University of Washington, Seattle, WA, USA.ORCID 0000-0003-1572-6181
Alan T MinDepartment of Statistics, University of Washington, Seattle, WA, USA.ORCID 0000-0001-9489-0478
Morgan O HammDepartment of Genome Sciences, University of Washington, Seattle, WA, USA.ORCID 0000-0003-4192-2688
Elliott SwansonDepartment of Genome Sciences, University of Washington, Seattle, WA, USA.ORCID 0000-0002-0351-6446
Danilo DubocaninDepartment of Genetics, Stanford University School of Medicine, Stanford, CA, USA.ORCID 0000-0003-0330-5814
Connor FinkbeinerDepartment of Genome Sciences, University of Washington, Seattle, WA, USA.
Tony LiDepartment of Genome Sciences, University of Washington, Seattle, WA, USA.ORCID 0000-0003-3546-123X
Dale WhittingtonDepartment of Medical Chemistry, University of Washington, Seattle, WA, USA.ORCID 0009-0004-0901-4481
William Stafford NobleDepartment of Genome Sciences, University of Washington, Seattle, WA, USA.ORCID 0000-0001-7283-4715
Andrew B StergachisDepartment of Genome Sciences, University of Washington, Seattle, WA, USA.ORCID 0000-0002-1299-3674
Mitchell R VollgerDivision of Medical Genetics, University of Washington School of Medicine, Seattle, WA, USA.ORCID 0000-0002-8651-1615

Funding

Northwest Genomics Center for All of UsOT2OD002748 · OD · UNIVERSITY OF WASHINGTON · PI EICHLER, EVAN, JARVIK, GAIL PAIRITZ · 2018 to 2023
$65.4M
Medical Genetics Training GrantT32GM007454 · NIGMS · UNIVERSITY OF WASHINGTON · PI Gail Pairitz Jarvik, Andrew Ben Stergachis · 1985 to 2026
$6.9M
Investigating the contribution of non-coding genetic variation to rare disordersDP5OD029630 · OD · UNIVERSITY OF WASHINGTON · PI STERGACHIS, ANDREW BEN · 2020 to 2024
$1.9M
Deep tensor genomic imputationR01HG011466 · NHGRI · UNIVERSITY OF WASHINGTON · PI NOBLE, WILLIAM STAFFORD · 2021 to 2024
$1.5M
NHGRI NIH HHS R01 HG011466NIGMS NIH HHS T32 GM007454NIH HHS DP5 OD029630NIH HHS OT2 OD002748
6 · The paper itself

Abstract

Long-read DNA sequencing has recently emerged as a powerful tool for studying both genetic and epigenetic architectures at single-molecule and single-nucleotide resolution. Long-read epigenetic studies encompass both the direct identification of native cytosine methylation as well as the identification of exogenously placed DNA

Identifiers

PMID37131601
PMCPMC10153250

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.