Evidence map›Paper›PMID 37131592›Full record

ArticleResearch square2023

Systematic Review: Emotion Dysregulation and Challenging Behavior Interventions for Children andAdolescents with Autism with Graded Key Evidence-Based Strategy Recommendations.

Heather J Nuske, Amanda V Young, Farzana Khan, Emma H Palermo, Bukola Ajanaku, Melanie Pellecchia, Giacomo Vivanti, Carla A Mazefsky, Lauren Brookman-Frazee, James C McPartland and 2 more

Open access · greenAbstract readPreprint
In one paragraph

Article in Research square, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Heather J NuskeUniversity of Pennsylvania.
Amanda V YoungUniversity of Pennsylvania.
Farzana KhanUniversity of Pennsylvania.
Emma H PalermoUniversity of Pennsylvania.
Bukola AjanakuUniversity of Pennsylvania.
Melanie PellecchiaUniversity of Pennsylvania.
Giacomo VivantiDrexel University.
Carla A MazefskyUniversity of Pittsburgh.
Lauren Brookman-FrazeeUniversity of California, San Diego.
James C McPartlandYale University.
Matthew S GoodwinNortheastern University.
David S MandellUniversity of Pennsylvania.
California University of Pennsylvania · USDrexel University · USUniversidad del Noreste · MXUniversity of California San Diego · USUniversity of Pittsburgh · USYale University · US

Funding

Reducing Challenging Behaviors In Children With Autism Through Digital HealthK01MH120509 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI NUSKE, HEATHER J · 2020 to 2024
$773k
NEUROBIOLOGY OF ANXIETY IN 5HT1A KNOCKOUT MICEF31MH012050 · NIMH · WEILL MEDICAL COLLEGE OF CORNELL UNIV · PI SIBILLE, ETIENNE L · 1998 to 1998
–
NIMH NIH HHS K01 MH120509NIMH NIH HHS N43 MH012050
6 · The paper itself

Abstract

Challenging behavior, such as aggression, is highly prevalent in children and adolescents with autism and can have a devastating impact. Previous reviews of challenging behavior interventions did not include interventions targeting emotion dysregulation, a common cause of challenging behavior. We reviewed emotion dysregulation and challenging behavior interventions for preschoolers to adolescents to determine which evidence-based strategies have the most empirical support for reducing/preventing emotion dysregulation/challenging behavior. We reviewed 95 studies, including 29 group and 66 single-case designs. We excluded non-behavioral/psychosocial interventions and those targeting internalizing symptoms only. We applied a coding system to identify discrete strategies based on autism practice guidelines with the addition of strategies common in childhood mental health disorders, and an evidence grading system. Strategies with the highest quality evidence (multiple randomized controlled trials with low bias risk) were Parent-Implemented Intervention, Emotion Regulation Training, Reinforcement, Visual Supports, Cognitive Behavioral/Instructional Strategies and Antecedent-Based Interventions. Regarding outcomes, most studies included challenging behaviors measures while few included emotion dysregulation measures. This review highlights the importance of teaching emotion-regulation skills explicitly, positively reinforcing replacement/alternative behaviors, using visuals and metacognition, addressing stressors proactively, and involving parents. It also calls for more rigorously-designed studies and for including emotion dysregulation as an outcome/mediator in future trials.

Identifiers

PMID37131592
PMCPMC10153364
OpenAlexW4366200124

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.