Evidence map›Paper›PMID 37131523›Full record

ArticleERJ open research2023

Functional respiratory complaints among COVID-19 survivors: a prospective cohort study.

Antoine Beurnier, Laurent Savale, Xavier Jaïs, Romain Colle, Tai Pham, Luc Morin, Sophie Bulifon, Nicolas Noël, Athénaïs Boucly, Benoit Delbarre and 24 more

Open access · goldAbstract read
In one paragraph

Article in ERJ open research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Bridging Gaps in Long COVID Therapy: A Review.Current medicinal chemistry · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors at 3 institutions in 2 countries.

Antoine BeurnierUniversité Paris-Saclay, Faculty of Medicine, Le Kremlin-Bicêtre, France.ORCID https://orcid.org/0000-0002-0481-3266
Laurent SavaleUniversité Paris-Saclay, Faculty of Medicine, Le Kremlin-Bicêtre, France.ORCID https://orcid.org/0000-0002-6862-8975
Xavier JaïsUniversité Paris-Saclay, Faculty of Medicine, Le Kremlin-Bicêtre, France.
Romain ColleUniversité Paris-Saclay, Faculty of Medicine, Le Kremlin-Bicêtre, France.
Tai PhamUniversité Paris-Saclay, Faculty of Medicine, Le Kremlin-Bicêtre, France.ORCID https://orcid.org/0000-0002-4373-0711
Luc MorinUniversité Paris-Saclay, Faculty of Medicine, Le Kremlin-Bicêtre, France.ORCID https://orcid.org/0000-0001-6721-4677
Sophie BulifonUniversité Paris-Saclay, Faculty of Medicine, Le Kremlin-Bicêtre, France.
Nicolas NoëlUniversité Paris-Saclay, Faculty of Medicine, Le Kremlin-Bicêtre, France.ORCID https://orcid.org/0000-0003-4055-617X
Athénaïs BouclyUniversité Paris-Saclay, Faculty of Medicine, Le Kremlin-Bicêtre, France.ORCID https://orcid.org/0000-0001-6246-5557
Benoit DelbarreAP-HP, Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Centre, Hôpital Bicêtre, DMU 5 Thorinno, Le Kremlin-Bicêtre, France.
Nathan EbsteinUniversité Paris-Saclay, Faculty of Medicine, Le Kremlin-Bicêtre, France.ORCID https://orcid.org/0000-0002-0458-9604
Samy FigueiredoUniversité Paris-Saclay, Faculty of Medicine, Le Kremlin-Bicêtre, France.
Matthieu GasnierUniversité Paris-Saclay, Faculty of Medicine, Le Kremlin-Bicêtre, France.
Anatole HarroisUniversité Paris-Saclay, Faculty of Medicine, Le Kremlin-Bicêtre, France.
Etienne-Marie JutantUniversité Paris-Saclay, Faculty of Medicine, Le Kremlin-Bicêtre, France.ORCID https://orcid.org/0000-0002-1374-1890
Mitja JevnikarUniversité Paris-Saclay, Faculty of Medicine, Le Kremlin-Bicêtre, France.
Sophia KeddacheUniversité Paris-Saclay, Faculty of Medicine, Le Kremlin-Bicêtre, France.
Anne-Lise LecoqUniversité Paris-Saclay, Faculty of Medicine, Le Kremlin-Bicêtre, France.ORCID https://orcid.org/0000-0002-8630-961X
Olivier MeyrignacUniversité Paris-Saclay, Faculty of Medicine, Le Kremlin-Bicêtre, France.ORCID https://orcid.org/0000-0002-9744-9095
Florence ParentUniversité Paris-Saclay, Faculty of Medicine, Le Kremlin-Bicêtre, France.
Jérémie PichonUniversité Paris-Saclay, Faculty of Medicine, Le Kremlin-Bicêtre, France.
Mariana PredaUniversité Paris-Saclay, Faculty of Medicine, Le Kremlin-Bicêtre, France.
Anne RocheUniversité Paris-Saclay, Faculty of Medicine, Le Kremlin-Bicêtre, France.
Andrei SeferianUniversité Paris-Saclay, Faculty of Medicine, Le Kremlin-Bicêtre, France.
Marie-France BellinUniversité Paris-Saclay, Faculty of Medicine, Le Kremlin-Bicêtre, France.
Thomas GilleINSERM U1272, Hypoxia and the Lung, UFR SMBH Léonard de Vinci, Université Sorbonne Paris Nord, Bobigny, France.ORCID https://orcid.org/0000-0002-1577-6595
Emmanuelle CorrubleUniversité Paris-Saclay, Faculty of Medicine, Le Kremlin-Bicêtre, France.
Olivier SitbonUniversité Paris-Saclay, Faculty of Medicine, Le Kremlin-Bicêtre, France.ORCID https://orcid.org/0000-0002-1942-1951
Laurent BecquemontUniversité Paris-Saclay, Faculty of Medicine, Le Kremlin-Bicêtre, France.
Xavier MonnetUniversité Paris-Saclay, Faculty of Medicine, Le Kremlin-Bicêtre, France.
Marc HumbertUniversité Paris-Saclay, Faculty of Medicine, Le Kremlin-Bicêtre, France.ORCID https://orcid.org/0000-0003-0703-2892
David MontaniUniversité Paris-Saclay, Faculty of Medicine, Le Kremlin-Bicêtre, France.ORCID https://orcid.org/0000-0002-9358-6922
and the Comebac Investigators
Comebac Investigators
Inserm · FRUniversité Paris-Saclay · FRAssistance Publique – Hôpitaux de Paris · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Dyspnoea is a common persistent symptom after COVID-19. Whether it is associated with functional respiratory disorders remains unclear. Methods: We assessed the proportion and characteristics of patients with "functional respiratory complaints" (FRCs) (as defined by Nijmegen Questionnaire >22) among 177 post-COVID-19 individuals who benefited from outclinic evaluation in the COMEBAC study ( Findings: In the COMEBAC cohort, 37 patients had significant FRCs (20.9%, IC95: 14.9-26.9). The prevalence of FRCs ranged from 7.2% (ICU patients) to 37.5% (non-ICU patients). The presence of FRCs was significantly associated with more severe dyspnoea, lower 6-min walk distance, more frequent psychological and neurological symptoms (cognitive complaint, anxiety, depression, insomnia and post-traumatic stress disorders) and poorer quality of life (all p<0.01). In the explanatory cohort, seven out of 21 patients had significant FRCs. Based on CPET, dysfunctional breathing was identified in 12 out of 21 patients, five out of 21 had normal CPET, three out of 21 had deconditioning and one out of 21 had evidence of uncontrolled cardiovascular disease. Interpretation: FRCs are common during post-COVID-19 follow-up, especially among patients with unexplained dyspnoea. Diagnosis of dysfunctional breathing should be considered in those cases.

Identifiers

PMID37131523
PMCPMC9969230
OpenAlexW4321611370

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.